DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and C34C12.7

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_497718.2	Gene:	C34C12.7 / 183201	WormBaseID:	WBGene00007926	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	48/234 - (20%)
Similarity:	85/234 - (36%)	Gaps:	65/234 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QNYKLKTEVKRTVSVASRRECFELCLGEN--DFTCRSANYDRTSGACELSELDRLTLAGSQAFQV 275
            :||.:......|.||..:.||..:||..:  ...|.||.:......|.:|:.:::|  ....|..
Worm    43 KNYWIVGHAFHTSSVQFKDECLRMCLTSSIRKAKCLSAMHVPNDDECVISDQNQVT--KPDLFIE 105

  Fly   276 ND--GS---DYLENHCVDEPNK------------------LCEFKRLPGRILKTV--------DS 309
            ||  |:   ::..|.|||.|:.                  :.||.:..|:..:.:        :|
Worm   106 NDTPGTFTVNFFRNICVDPPDAEGVDRFEARLQGYKGGEGIIEFAQAVGKNTQVMVVISGLKENS 170

  Fly   310 VYQEVSSIDECRELCLNSPYRCHSYD-YNDTGD--MVCRLSHHSRATLADVQEPF---------- 361
            :| |::.:.:.:|    ...:||... .|..|.  |:....|...|.     ||:
Worm   171 LY-EINFLPDTKE----KGGQCHRKSRVNGEGKTLMIVETDHTGMAV-----EPWKVIDFDGFEE 225

  Fly   362 ------LEVPEASTYELTSCYNVTIECGGGDMLARIRTS 394
                  :.|.|.||..:..|.::.:.....:. :..|||
Worm   226 NVISKTIVVVEKSTQTIVDCGSIRLATASSNS-STTRTS 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532	19/78 (24%)
		PAN_1	294..373	CDD:278453	20/105 (19%)
		ZP	381..615	CDD:214579	3/14 (21%)
C34C12.7	NP_497718.2	PAN_AP_HGF	36..107	CDD:238532	16/65 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000