DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment neo and C30H6.5

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001255948.1	Gene:	C30H6.5 / 183068	WormBaseID:	WBGene00007823	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	76/379 - (20%)
Similarity:	123/379 - (32%)	Gaps:	109/379 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LALMLYS---AATAKEHLRIRRQAAESVTAAAPNASKVMASEEIKDKTEWPGAKETSTEINRTER 73
            |.:.||.   |:|..|.:|:.....::.|.:||..:.::.:..:.......|. .|:..|:.|::
Worm   151 LQIDLYENRCASTENETVRLAVFTEQTRTTSAPVRTSIVGNVIMAPVPNLNGT-TTNAPISTTQQ 214

  Fly    74 PVENVETRNSGFDLPAASDLSSSLGSEE-------------DSIYYDNAPVDCNPELVGFEIVTG 125
            .:            |..::|......::             .::|.|..........|.......
Worm   215 AI------------PTTNELRRVHAVKQYPLDPKNGNVIFSKTVYADQPSPPLPQRFVDRRNRNA 267

  Fly   126 YVFSAPEKLMDSQPGTLMLTDCLDTCRKNKTCQSVNYETGLCVLFSAHADQLPGALTK-----SQ 185
            .:|.:|..|:||....:....           |.|..::.:            |:|||     |:
Worm   268 KIFLSPRPLVDSTSSVVAAAQ-----------QQVQLQSDV------------GSLTKERRQRSE 309

  Fly   186 FPVF--TIYAQKSCLAVKPCSRAWYVDRVQNYKLKTEVKRTVSVASRRECFELCLGE-NDFTCRS 247
            .||.  .:.....|....|       :|:.:   |.|..| :...:...|...|... .:|.|.|
Worm   310 RPVVLENLAVPAGCFIKTP-------NRILH---KFEESR-IGGVTLETCMRQCAQSLQNFYCAS 363

  Fly   248 ANYD-------RTSGACELSELDRLTLAGSQAFQVNDGSDYLENHCVDEPNKLCEFKRLPGRILK 305
            .||.       ...|...|:..|  ||.||:.|      ||.||.|  :|           |...
Worm   364 INYSFGLKICILNGGNLHLNGGD--TLVGSREF------DYFENTC--QP-----------RSTT 407

  Fly   306 TVDSVYQEVSSIDECRELCLNSPYRCHSYDYNDTG--------DMVCRLSHHSR 351
            |.:|......:..||..|..||.|  :|:|....|        :..|..||..|
Worm   408 TTESSIGGSGTKKECYRLYNNSIY--NSFDATIVGGLQDLESCESECSWSHIRR 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	14/83 (17%)
		PAN_AP_HGF	211..285	CDD:238532	22/81 (27%)
		PAN_1	294..373	CDD:278453	16/66 (24%)
		ZP	381..615	CDD:214579
C30H6.5	NP_001255948.1	PAN_AP_HGF	80..159	CDD:238532	3/7 (43%)
		PAN_AP_HGF	323..400	CDD:238532	24/95 (25%)
		PAN_AP	422..488	CDD:214680	12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100