DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and ZC449.1

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_508855.1	Gene:	ZC449.1 / 180775	WormBaseID:	WBGene00022611	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	88/321 - (27%)
Similarity:	125/321 - (38%)	Gaps:	64/321 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 AKETSTEINRTERPVENVETRNSGFD-LPAASDLSSSLGSEEDSIYYDNAPVDCNPELVGFEIVT 124
            ||..|:.:.|.|...|.:.::..|.: |...|...:..|.|.|..  :|.|:.|... .|:.:|.
Worm   161 AKAMSSPMVRMEDMDEVLRSKLRGEESLVPMSQKDTEEGKELDKT--ENGPLKCKTS-SGYYVVV 222

  Fly   125 GYVFSAPEKLMDSQP-GTLMLTDCLDTCRKNK-------TCQSVNY--ETGLCVLFSAHADQLP- 178
            |.....|....|.|. ..:...||...|.:||       .|:|:||  ....|.|:...|:  |
Worm   223 GNEIVLPISGGDVQVYNEVEQGDCAKYCSENKGPDGSTINCRSLNYFPVEKKCELYGILAE--PH 285

  Fly   179 --GALTKSQFPVFTIYAQKSCLAVKP--CSR-AWYVDRVQNYKLKTEVKR----TVSVASRRECF 234
              |.|.:::   ..|||:|.||...|  |.. ..::..||    ||..||    |.:.:|..:|.
Worm   286 GSGKLLENE---KVIYAEKFCLPESPFVCQNDEIFILHVQ----KTLSKRRRITTKAASSITDCL 343

  Fly   235 ELCLGENDFTCRSANYDRTSGACELSELDRLTLAGSQAFQVNDGSDYLENHC---------VDEP 290
            ..||.::|  |||:.|...|..|||..:|..|  |..|...:..:..:||.|         .|.|
Worm   344 RKCLEQDD--CRSSVYISNSKKCELHNVDVST--GDYARDSDRETVLIENGCRRKGVTPKRKDSP 404

  Fly   291 NKLCEFKRLPGRILKTVDSVYQEVSSID----ECRELCLNSPYRCHSYDYNDTGDM---VC 344
            :.        ..||.|..|..:..|..:    ||.........|..:   ||.|||   ||
Worm   405 SL--------SSILDTSSSESESSSPSNGGWSECDYKINGETVRVRT---NDDGDMETEVC 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	24/89 (27%)
		PAN_AP_HGF	211..285	CDD:238532	25/77 (32%)
		PAN_1	294..373	CDD:278453	15/58 (26%)
		ZP	381..615	CDD:214579
ZC449.1	NP_508855.1	PAN_AP	21..105	CDD:214680
		PAN_1	230..303	CDD:278453	21/77 (27%)
		PAN_1	317..391	CDD:278453	26/81 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010