DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and ZC449.2

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_508854.2	Gene:	ZC449.2 / 180774	WormBaseID:	WBGene00022612	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	252	Identity:	56/252 - (22%)
Similarity:	93/252 - (36%)	Gaps:	72/252 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 ELVGFEIVTGYVFSAPEKLMDSQPGTLMLTDCLDTCRKNKT-------CQSVNYE--TGLCVLFS 171
            |.:.:.:|.|...|.  |::..:...:..:.||..|.:|..       |.|:|||  ..:|.::
Worm   222 ETLSYFLVYGSRLST--KMLPQRLNGVDQSSCLMYCSQNINAIGQNIPCYSLNYEPTNEICEMY- 283

  Fly   172 AHADQLPGALTKSQFPVFTI-------YAQKSCLAVKPCSRAWYVDRVQNYK--LKTEVKRTVSV 227
                   |..|:::....|:       :..|.|:..|....|..:..|..||  :|..:.|...:
Worm   284 -------GEQTRNESDSATLAIDDEHNFGDKFCIKTKYHCDAETLYPVHLYKKLMKNIIARVPGL 341

  Fly   228 ASRRECFELCLGENDFTCRSANYDRTSGACEL-----SELDRLTLAGSQAFQVNDGSDYLENHCV 287
            ||:..|...|:...:  |::..|  .:|.|.|     ||.:.|.|.||....|      :||.|.
Worm   342 ASKISCLSECIENRE--CKAVTY--KNGMCVLHSVSPSEDESLLLDGSGKTMV------IENGCH 396

  Fly   288 DEPN----------------------KLCEFKRLPGRILKTVDSVYQEVSSIDECRE 322
            ...|                      .||:: .:.||.::    |.|.  ..|:|.|
Worm   397 VSSNTNKSVTKSKEDSEESESSWQEWSLCQY-GVKGRKMR----VRQR--ECDDCEE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	18/92 (20%)
		PAN_AP_HGF	211..285	CDD:238532	22/80 (28%)
		PAN_1	294..373	CDD:278453	8/29 (28%)
		ZP	381..615	CDD:214579
ZC449.2	NP_508854.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000