Protein Alignment neo and rocf-1

DIOPT Version :10

• Sequence 1: NP_651733.1
• Gene: neo / 43523
• FlyBaseID: FBgn0039704
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_506848.1
• Gene: rocf-1 / 180041
• WormBaseID: WBGene00011948
• Length: 1262
• Species: Caenorhabditis elegans
• Alignment Length: 698
• Identity: 147/698 - (21%)
• Similarity: 220/698 - (31%)
• Gaps: 207/698 - (29%)

  Fly    36 VTAAAPNASK----VMASEEIKDKTEWP--GAKETSTEINRTERPVENVETRNS---GFDLPAAS 91
            :||:.|:...    :....|....|..|  .|:.|....:.|.||  ...|||:   |.::|  :
 Worm   656 MTASTPSGKNPPTYIPLHPETSQSTPTPTTSARSTRPTASVTRRP--EFPTRNTPPFGGNVP--N 716

  Fly    92 DLSSSLGSEEDSIYYDNAPVDCNPELVGFEIVTGYVFSAPEKLMDSQPGTLMLTDCLDTCRKNKT 156
            ..||::            |...||...|:   ...||:..||   :..|..::|         .|
 Worm   717 GPSSTV------------PPASNPTTEGY---FTQVFTDREK---TNSGESVVT---------TT 754

  Fly   157 CQSVNYETGLCVLFSAHADQLPGAL-------------TKSQFPVFTIYAQKSCLAVKPCSRAWY 208
            ..|.:.||.....||.......|.:             |.|.||..:.
 Worm   755 ASSTDSETPGSGSFSTSPQTTAGWIYTSTDATPESEYSTASSFPTLST----------------- 802

  Fly   209 VDRVQNYKLKTEVKRTVSVASRRECFELCLGEND--------FTCRSANYDRTSGACELSELDRL 265
            .||....:.....:.|..:....|.||......|        ||.|....:..:.....|.
 Worm   803 SDRFTPSESSRSTETTTVITPFTETFESSTLTPDQFEDVTSTFTDRFRPSEYATSPTPPSP---- 863

  Fly   266 TLAGSQAFQVNDGSDYLENHCVDEPNKLCEFKRLPGRILKTVDSVYQEVSSIDECRELCLNSPYR 330
            |...:.:|..|:||.                   ||.:..|                   |.|.|
 Worm   864 TRVVTASFPPNEGSS-------------------PGILPST-------------------NPPPR 890

  Fly   331 CHSYDYNDTGDMV-CRLSHHSRATLADVQEPFLEVPEASTYELTSCYNVTIECGGGDMLARIRTS 394
            .:.|...:....| .||....|         .|.:.:..::|:.:...:|.|....|....:...
 Worm   891 NNPYAPPEGAPRVPNRLIGKPR---------ILCLEDGISFEVKTILPLTGEVFANDRKRVLECH 946

  Fly   395 KLFNGKVYAKGSPKSCSVDVKSALDFELRMNYHDLECNVRQSTAGRYVNDIIIQHHDMIVTSSDL 459
            |.|.    .:..|       |..|.|.        .|.|:  ..|..| |...|:|..:|...|.
 Worm   947 KSFT----EEAKP-------KMFLPFS--------TCGVK--NVGEQV-DSRAQYHMQVVLIIDQ 989

  Fly   460 GLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVE-------------SPNVIMRITSRDGS 511
            |...........:.|...|:.:.:  ::|...||.:.|             .|:|.|:|...:|.
 Worm   990 GNGTNTLQSFMAQCVHQKVNYNKQ--VLPKRIEEALEELRLVPSKLEQKASMPSVQMQIVVDEGH 1052

  Fly   512 DMM----RSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEITLIDSNGCPTD------- 565
            ..:    .:|::|.|||||:.:|.|...|.:.||....:|.|...:.||||..||..|
 Worm  1053 HKLGAEVSAADIGMPLALKWSMVPESDAYGMHIRNCKVVDAVGKIDHTLIDEQGCSADLQIIDHP 1117

  Fly   566 HFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPC---------MPSCE----PVQCEQ 617
            |:   ..|..:.|..|.     |||.|....:|.:..:..|         ..|||    |..|..
 Worm  1118 HY---DTYHDTASSHMW-----AFKVPDMSSLQIKCDILICSNIKSSVTNTTSCEDIPSPPFCAD 1174

  Fly   618 EDTSGEFRSLL----SYGRKRRSLNTTDDHPRP---RRDIDTSKKSAP 658
            ..||.. .|:|    |:.:.||:...::..|..   |..|..||...|
 Worm  1175 VVTSPP-NSILSDASSFIKHRRASVPSEVSPATQSVRTSICLSKSCRP 1221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:459635	17/89 (19%)
		PAN_AP_HGF	211..285	CDD:238532	15/81 (19%)
		PAN_1	294..373	CDD:459635	13/79 (16%)
		ZP	381..615	CDD:214579	64/270 (24%)
rocf-1	NP_506848.1	PHA03247	<561..909	CDD:223021	65/342 (19%)
		ZP	915..1156	CDD:214579	62/272 (23%)