DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-26

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_741299.2	Gene:	cutl-26 / 176896	WormBaseID:	WBGene00021950	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	58/244 - (23%)
Similarity:	109/244 - (44%)	Gaps:	30/244 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 IRTSKLFNGKVYAKGS-PKSCSVDVKSALDFELRMNYHDLECNVRQSTAGR-YVNDIIIQHHDMI 453
            |||||.|.|.|..:.| .::|.|.........|::|....||.::...|.: |...:.:..|.::
Worm    42 IRTSKPFEGLVQTRSSESEACRVQGFGTNVAVLKLNLKSDECGIKYDVASKTYSVTVDVHSHPVL 106

  Fly   454 VTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVESPNVIMRI-TSRDGSDMMRSA 517
            :...|..:.:.|      :.::||..         ..:.::..:|.:..:|: :||...|.::.:
Worm   107 IVEGDKSVNVTC------REIANGTQ---------HYASQMTSQSSDYQLRVLSSRLPVDTVKYS 156

  Fly   518 EVGDPLALKFEIV--DEQSPYEIFIRELVAMDGVDNSEITLIDSNGCPTDHFIMGPI-YKGSVSG 579
            :   |..|:...:  .:|:.|..|:.:.:|.....|..:.|.|..||.....|||.. .:.||..
Worm   157 Q---PYTLQIRPLPSTQQNSYSFFVGQCIAQPVGGNVTVQLTDPVGCALFKSIMGHFARRESVEE 218

  Fly   580 KMLLSNFDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSGEFRSLL 628
            ..:.|   .|:||:::.::...:||.|..|||...|:|:.::.   |||
Worm   219 AEIPS---MFRFPNAKQLKISCIVTECDGSCEARTCDQDSSAS---SLL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	53/229 (23%)
cutl-26	NP_741299.2	Zona_pellucida	33..252	CDD:391783	53/230 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010