Protein Alignment neo and cutl-28

DIOPT Version :9

• Sequence 1: NP_651733.1
• Gene: neo / 43523
• FlyBaseID: FBgn0039704
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_499971.2
• Gene: cutl-28 / 176895
• WormBaseID: WBGene00018256
• Length: 696
• Species: Caenorhabditis elegans
• Alignment Length: 690
• Identity: 160/690 - (23%)
• Similarity: 282/690 - (40%)
• Gaps: 131/690 - (18%)

  Fly   133 KLMDSQPGTLMLTDCLDTCRKNKTCQSVNYETGLCVL-----FSAHADQLPGALTKSQFPVFT-- 190
            |.:||      |:.|...|.....|....:.....:.     |:.|        ..|:.||.|
 Worm    43 KSVDS------LSQCTRFCSSVPNCTHFTFSNAEPIEKKNGGFNCH--------LHSKSPVLTTS 93

  Fly   191 ---IYAQKSCLAVKPCSRAWYVDRVQNYKL--KTEVKRTVSVASRRECFELCLGENDFTCRSANY 250
               ....|:||..|...|::..::.....|  .:.:.:|.|: |..||...|  :.:.:||:|.:
 Worm    94 GSRTVGTKTCLENKCLKRSFAFEKFPGRSLVNSSFIIKTFSI-SMEECLSQC--QKESSCRAALH 155

  Fly   251 DRTSGACELSELDRLTLAGSQA-FQVNDGSDYLENHCVD--EPNKLCEFKRLPGRILKTV-DSVY 311
            :..:..|:||.:...::...:. |:.:...|..||:|||  ..:..|.|.|:.|..||:| |.:.
 Worm   156 NNDTSLCQLSRVSLNSVYNPRLYFKASYSVDLYENNCVDYAMTSSACTFMRVNGGGLKSVSDQLI 220

  Fly   312 QEVSSIDECRELC-LNSPYR--CHSYDY-NDTGDMVCRLSHHSRATLADVQEPFLEVPEASTY-- 370
            |.|.|.|||.::| :.|...  |.||.| |.|.:  |.|...|...|.  :.| ||..:.:.:
 Worm   221 QNVGSFDECEQMCVIRSRISDVCRSYTYDNSTNE--CNLMWASARMLG--RSP-LESMKPNLFHG 280

  Fly   371 ELTSCYNVTIECGGGDMLARIRTSKLFNGKVYAKGSPK-SCSVDVKSALDFELRMNYHDLECNVR 434
            :|..|.|.:::|...::..:..:.::|.||:..|.|.| .|..|.:...||..:.::.....:..
 Worm   281 DLDDCVNFSLKCREDNLEVKASSMRMFIGKMMTKKSKKIMCQEDYEGNYDFSSKFDFKKCGLDPN 345

  Fly   435 QSTAGRYVNDIIIQH-HDMIVTSSDLGLALACQYDLTNKSVSN-----GVDLDVR--GDIMPALS 491
            :|....|...:.::. ...:||..|..|.:.|:   .:||:.:     .|.::||  ......:|
 Worm   346 KSKDSTYRGMVHVKEGSTSLVTIRDKVLQVNCR---LHKSMPSEEQFLSVQMNVRENNKTNQVMS 407

  Fly   492 EEVIV------ESPNVIMRITSRDGSDMMRSAEVGD----PLALKFEIVDEQSPYEIFIRELVAM 546
            :.|:|      .:|...::|...|.:: ..:..:||    .||:|      .|..:..:..|||.
 Worm   408 DVVVVTAPPAQTNPKFSLKILGLDSTE-ADTVHIGDYGWIMLAVK------NSAEDFTVTNLVAK 465

  Fly   547 DGVDNSEITLIDSNGCPTDHFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPCMPSCE 611
            |......:.:||.:||.....|:..|.|.....|:.:| |..|: ..:||| :.|::..|...|.
 Worm   466 DVQTGRVLRIIDEDGCVLRRDIVKEIRKTDNYVKLKIS-FSGFR-RQTEVV-YHAMMETCTVGCM 527

  Fly   612 PVQCEQEDTSGEFRSLLSYGRKRRSLNTTDDHPRPRRDIDTSKKSAPSDMLLVQSI-QIT----- 670
            | :|.|:....|..:.:      .||..:.|.|| .|.:..|....|.::.|...: ::|
 Worm   528 P-KCNQDMMLPEEETNV------HSLPLSLDLPR-HRMVRRSLAGEPRELQLTSDVYKVTGHKLT 584

  Fly   671 -------DKFGFKQDK-----QESGDFYDG-------NETTFTANEEGHGFCVNAIGLITAATIF 716
                   .:|.|...|     .::|:|::|       :...:|:.:.    |     ||...|..
 Worm   585 LLNPPSPKQFDFPAPKSDFEFNDNGEFHEGDVIVVKHSPNLWTSVKH----C-----LIDDVTCM 640

  Fly   717 LLTQLAVIAIW--------TYCYQR-----RQKLQPYQHS 743
            |...|..|.::        .|||.:     |:..:|.:|:
 Worm   641 LTVVLGAIQMFLMFSCFLIMYCYYQQWRFYRELNRPQEHN 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	14/73 (19%)
		PAN_AP_HGF	211..285	CDD:238532	16/76 (21%)
		PAN_1	294..373	CDD:278453	29/85 (34%)
		ZP	381..615	CDD:214579	57/252 (23%)
cutl-28	NP_499971.2	APPLE	30..103	CDD:128519	14/73 (19%)
		PAN_1	114..192	CDD:278453	17/80 (21%)
		PAN_1	202..292	CDD:278453	32/94 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I3502
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_115610
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17004
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.850