DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-2

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_496097.1	Gene:	cutl-2 / 174532	WormBaseID:	WBGene00013145	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	70/291 - (24%)
Similarity:	121/291 - (41%)	Gaps:	40/291 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 IECGGGDMLARIRTSKLFNGKVYAKGS--PKSCSVDVKSALDFELRMNYHDLEC---NVRQSTAG 439
            |.|....:...:.|...|.|.::.:||  .|||..:..:.....:...:...:|   ..||..|.
Worm    27 IRCAPTGITIMLETDSPFKGALFLRGSADKKSCKANFSAQPSQNISFEFGFDDCPSRRKRQIVAP 91

  Fly   440 RYV---NDIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLD-----VRGD--IMPALSEEV 494
            |.:   :.:::.:|..|:|..|:...:.|.|...|..|...:.::     :..|  .:|.....|
Worm    92 RGMTMSSVLVVSYHGSIITHRDVAYQIDCFYREENSRVETMLSVNAPQPRILSDEPKLPTCDYRV 156

  Fly   495 IVESPNVIMR--ITSRDGSDMMRSAEVGDPLALKFEIVDEQSPYEIF---IRELVAMDGVDNSEI 554
            .|.....:..  :||.......:.|.|||.: :........:|.:::   :....|.|| .:..:
Worm   157 EVTGGKAVAGGIVTSSLSETASQIANVGDSV-IHIWTCSGDAPSDVYCIQVYSCTAEDG-GSDTV 219

  Fly   555 TLIDSNGCPTDHFIMGPI-YKGSVSGKM-LLSNFDAFKFPSSEVVQFRA--LVTPCMPSCE-PV- 613
            .::|.|||.||..::.|| ||   .|.| ..::..||||..:.:|.|:.  .:|...||.| ||
Worm   220 QVVDENGCTTDGELLSPIKYK---EGSMRAAASSHAFKFVDNHIVYFKCNIRITVKNPSGECPVN 281

  Fly   614 QCEQEDTSGEFRSLLSYGRKRRSLNTTDDHP 644
            .|....::|    |:|  ||.|.:   .:||
Worm   282 NCSPNGSTG----LIS--RKARDV---FEHP 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	60/259 (23%)
cutl-2	NP_496097.1	ZP	28..286	CDD:214579	61/262 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910