DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cut-3

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_495780.1	Gene:	cut-3 / 174347	WormBaseID:	WBGene00009041	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	391	Identity:	78/391 - (19%)
Similarity:	151/391 - (38%)	Gaps:	91/391 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 IECGGGDMLARIRTSKLFNGKVYAKG--SPKSCSVDV--KSALDFELRMNYHDLECNVRQSTA-- 438
            :|||...:.....|...|.|.||.||  ..:.|..|.  :.....||..:    .|||.::.:
Worm    32 VECGPTSITVNFNTRNAFEGHVYVKGLFDQQECRNDEGGRQVAGIELPFD----TCNVARTRSLN 92

  Fly   439 --GRYV-NDIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVESPN 500
              |.:| ..:::..|...||..|....:.|.|...:|:||..:::   .|:..|...:|:   |.
Worm    93 PKGVFVTTTVVVSFHPQFVTKVDRAYRVQCFYMEADKTVSTQIEV---SDLTTAFQTQVV---PM 151

  Fly   501 VIMRITSRDGSDMMRSAEVGDPLALKFEIVDEQ------------SPYEIFIRELVAMDGVDNSE 553
            .|.:.      :::.....|:|  ::|..:.:|            ..:...:......|| :...
Worm   152 PICKY------EILNGGPTGEP--VQFATIGQQVYHKWTCDSETVDTFCAVVHSCTVDDG-NGDT 207

  Fly   554 ITLIDSNGCPTDHFIMGPI-YKGSVSGKMLLSNFDA--FKFPSSEVVQFRALVT--------PC- 606
            :.::|.|||..|.|::..: |...     |::..:|  :|:.....:.::..::        .|
Worm   208 VQILDENGCALDKFLLNNLEYPTD-----LMAGQEAHVYKYADRSQLFYQCQISITVKEPNEECA 267

  Fly   607 MPSCEPVQ----CEQEDTSGEFRSLLSYGRKRRSLNTTDDHPRPRRDIDT---SKKSAPSDMLLV 664
            .|:|...|    .:|.:.:.:|..:|    |:||....::....|.::.|   .:.:.||.:...
Worm   268 RPTCSEPQGFGAVKQANQTAQFFRVL----KKRSAPVMENILDVRAELTTLEVLEGNLPSSLTQA 328

  Fly   665 QSIQITDKFGFKQDKQESGDFYDGNETTFTANEEGHGFCVNAIGLITAATIFL-LTQLAVIAIWT 728
            |::..:.:.|....:||                    .|:::.. |:..|:|| ||....|.| |
Worm   329 QALVASREIGEDSFRQE--------------------LCISSFH-ISVVTVFLGLTVFVAIFI-T 371

  Fly   729 Y 729
            |
Worm   372 Y 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	53/270 (20%)
cut-3	NP_495780.1	ZP	33..272	CDD:214579	51/262 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910