DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-16

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_495296.2	Gene:	cutl-16 / 174065	WormBaseID:	WBGene00019426	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	81/303 - (26%)
Similarity:	116/303 - (38%)	Gaps:	56/303 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 IECGGGDMLARIRTSKLFNGKVYAKG--SPKSCSVDVKSALDFELRMNYHDLECNV-RQSTAG-- 439
            :.|..|.|..::.|.|.....|:.||  ....||....:...||..      :|:| ||..|.
Worm    33 VSCHSGFMSLKVNTEKSPPSHVFVKGHFRKDGCSFSNTANATFEFS------KCDVMRQREANPK 91

  Fly   440 --RYVNDIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVESPNVI 502
              .|...:::|.|.:..|..|....|.|.|....|:|  |.::.| .|..|...|:   |||..:
Worm    92 GMAYTATVVVQLHPLFTTKVDRAYKLRCFYKEAEKAV--GAEVSV-SDPTPVQLED---ESPQPV 150

  Fly   503 MRITSRDGS---DMMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEIT--LIDSNGC 562
            ...|....|   .:.:.|::||.|...:|     .|.|.:..|:...|.|...|.:  :|..|||
Worm   151 CSYTIHKESPNGPIAKFAQLGDVLYHVWE-----CPSEAYQMEVYNCDVVGGEEYSKKVIGENGC 210

  Fly   563 PTDHFIM-GPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPC--------MPSCEPVQCEQE 618
            ..|.:|| ..||..:.:...:.||  ||.||....|:....::.|        .|.|:......:
Worm   211 SEDIYIMPNLIYNENRTKAFVNSN--AFNFPDQNNVRISCKISVCPTLSGTCHQPKCDASASSID 273

  Fly   619 DTSGEFRSLLSYGRK--RRSLNTTDDHPRPRRDIDTSKKSAPS 659
            |.|...      ||:  |..|.||   |.|     ||....||
Worm   274 DASEPI------GRELARDELITT---PMP-----TSSTEIPS 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	67/254 (26%)
cutl-16	NP_495296.2	ZP	35..268	CDD:214579	67/251 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910