DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-10

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_492900.1	Gene:	cutl-10 / 173021	WormBaseID:	WBGene00013180	Length:	403	Species:	Caenorhabditis elegans

Alignment Length:	420	Identity:	84/420 - (20%)
Similarity:	159/420 - (37%)	Gaps:	95/420 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 EVPEASTYELTSCYNVTIECGGGDMLARIRTSKLFNGKVYAKG--SPKSCSVDVKSALDFELRMN 425
            |:||             ::|....:....:|.:.|:|:::.||  ..::|..|..::...::...
Worm    29 ELPE-------------VDCMEDRVKLSFKTQRPFHGRIFVKGMVDKQACVRDFVTSQAKDVTFE 80

  Fly   426 YHDLECNVRQ------STAGRYVN-DIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDV- 482
            ..:..||:|:      ...|..:: .:||..|...:|..|......|.|...:|.|:|..|:.:
Worm    81 LENGACNMRRQRMLGPEKRGMEMSMTVIISFHSTFITKVDRAYRCTCFYMEADKVVTNKFDVSML 145

  Fly   483 -RGDI-----MPALSEEVIVESPNVIMRITSRDGSDMMRSAEVGDPLALKFEIVD-EQSPYEIFI 540
             ..|:     ||..:..|..:|      ||    ..::..|:||:.:   :.:.: |...:.:.:
Worm   146 PTTDLIDTARMPLCTYSVRRDS------IT----GPIVEFAKVGETV---YHVWNCESDMFSMLV 197

  Fly   541 RELVAMDGVDNSEITLIDSNGCPTDHFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTP 605
            ......||..:....|:|.:||..|..|: |....:....:..:..:.|||.......|:..|:.
Worm   198 HSCFVDDGNGDERKPLLDEHGCAIDPLIL-PDLTYNKDNNVAYAQVNTFKFADKVSTYFQCAVST 261

  Fly   606 CM-----------PSCEPVQCEQEDTSGEFRSLLSYGRKRRSLNTTDDHPRPRRDIDTSKKSAPS 659
            ||           |.|.|        :|.|          ||.::::|:...||    |:::..|
Worm   262 CMNTEGMCDGKTPPRCGP--------AGSF----------RSSSSSNDNGFNRR----SRRATLS 304

  Fly   660 DMLLVQSIQITDKFGFK---------QDKQESGDFYDGNETTFTANEEGHG----FCVN--AIGL 709
            :...|..:.:.|.....         ::||.|.|..:....:..|..:|..    .|:|  .|.:
Worm   305 NRTAVNWVHLADTMDLAANKITVFELEEKQNSEDKDEPPAHSHLAILQGSHPSTVVCLNQSRIQI 369

  Fly   710 ITAATIFLLTQLAVIAIWTYCYQRRQKLQP 739
            ....:..:||.:.|:.|:|.   ||....|
Worm   370 FFVLSFLMLTVVTVLTIFTV---RRSMTAP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453	3/9 (33%)
		ZP	381..615	CDD:214579	53/261 (20%)
cutl-10	NP_492900.1	ZP	35..279	CDD:214579	52/257 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910