Protein Alignment neo and noah-1

DIOPT Version :10

• Sequence 1: NP_651733.1
• Gene: neo / 43523
• FlyBaseID: FBgn0039704
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_740859.3
• Gene: noah-1 / 172261
• WormBaseID: WBGene00016422
• Length: 1052
• Species: Caenorhabditis elegans
• Alignment Length: 823
• Identity: 172/823 - (20%)
• Similarity: 297/823 - (36%)
• Gaps: 228/823 - (27%)

  Fly    90 ASDLSSSLG-----SEEDSIYYDN----APVDCN--------PE--LVGFEIVTGYVFSAPEKLM 135
            |.:.|..||     :.|...|::.    :|..|.        |:  ||||...          :|
 Worm   258 ADERSKPLGRADLIATEGFTYFEKKCFASPNTCRNVPSFKRVPQMILVGFAAF----------VM 312

  Fly   136 DSQPGTLMLTDCLDTCRK-------NKTCQSV--NYETGLCVLFSAHADQLPGALTKSQFPVFTI 191
            ::.|...|   |||.|..       ...|:||  .|....|:|.|...:..|.............
 Worm   313 ENVPSVTM---CLDQCTNPPPETGDGFVCKSVMYYYNEQECILNSETRESKPELFIPEGEEFLVD 374

  Fly   192 YAQKSC-LAVKPCSRAWYVDRVQNY-------KLKTEVKRTVSVASRRECFELCLGENDFTCRSA 248
            |...:| |..:.|....::..::..       :.:..|.:..:....:||...|.|.....|||.
 Worm   375 YFDITCHLKQEKCPTGQHLKAIRTINAALPEGESELHVLKASAAKGIKECVAKCFGLAPEKCRSF 439

  Fly   249 NYDRTSGACELSELDRLTLAGSQAF--QVNDGSDYLENHCV------------DEPNKLCEFKR- 298
            |||:.:.:|:|..||     |....  ||..|.|..:.||:            ::.:.|  |.|
 Worm   440 NYDKKTKSCDLLYLD-----GHNTLQPQVRQGVDLYDLHCLAAMPLVENDCSANKDDAL--FSRY 497

  Fly   299 -------LPGRILKTVDSVYQEVSSIDECRELCLNSPYRCHSYDYN------------------- 337
                   :|.::.|.|        |::.|.|:|..:| .|...:||
 Worm   498 LHTKQRGIPAKVYKVV--------SLNSCLEVCAGNP-TCAGANYNRRLGDCTLFDAIDDDAEIN 553

  Fly   338 ---------------DTGDM----VCRLSHHSRATLAD-------------VQEPFLE------V 364
                           |||..    |....|....|:.:             |::|.::      .
 Worm   554 EHTDFYKNLCVTKEIDTGASAAANVPETKHRVSGTVVEGKDSKSQLLATKKVKKPTIKNTEHRRA 618

  Fly   365 PEASTYELTSCYNVTIE-----CGGGDMLARIRTSKLFNGKVYAKGSPKSCSVDVKSA------- 417
            || ||..:.....|..|     |....:..:|...:.|:|.::.|....:|.|:|.::
 Worm   619 PE-STVPIGPPVEVKAEAIQTICNYEGIKVQINNGEPFSGVIFVKNKFDTCRVEVANSNAATLVL 682

  Fly   418 ---LDFELRM----NYHDLE--------------------------------CNVRQSTAGRYVN 443
               .||.:|.    |..|.|                                |.:.....|.|.:
 Worm   683 GLPKDFGMRPISLDNIDDNETGKNKTKKGEETPLKDEIEEFRQKRQAAEFRDCGLVDLLNGTYKS 747

  Fly   444 DIIIQHHDM----IVTSSDLGLALACQY-DLTNKSVSNGVDLDVRGDIMPALSEEVIVESPN-VI 502
            .::||.:::    :|||.|....::|.| .:....|..|.::.|.|.....:.....:|..| |:
 Worm   748 TVVIQTNNLGIPGLVTSMDQLYEVSCDYSSMLGGRVQAGYNMTVTGPEANLIQPRGKIELGNPVL 812

  Fly   503 MRITSRDGSDM-MRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGV------DNSEITLIDSN 560
            |::.:.||::. :..|::||.|.|::||:......:.|::...|..||      ...::.||| .
 Worm   813 MQLLNGDGTEQPLVQAKLGDILELRWEIMAMDDELDFFVKNCHAEPGVAGGKAGAGEKLRLID-G 876

  Fly   561 GCPTDHFIMGPIYKGSV---SGKMLLSNFDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSG 622
            ||||. .:...:..|::   |..:..:...||:|.||..::....|..|...||||:|..  |.|
 Worm   877 GCPTP-AVAQKLIPGAIEIKSSAVKTTKMQAFRFDSSASIRVTCEVEICKGDCEPVECAL--TGG 938

  Fly   623 EFRSLLSYGRKRRSLNTTDDHPRPRRDIDTSKKSAPSDMLLVQSIQITDKFGFKQDKQESGDFY- 686
            ..:   |:|||:|.::...:.....|.:...:..|.:.::::..:|..:: .....:..:.|..
 Worm   939 VKK---SFGRKKREVSNNIEEFETNRYLIPRRSHATTSIVIIDPLQQVNE-PVAMSRASTLDLLR 999

  Fly   687 -DGNETTFTANEEGHGFCVNAI---GLITAATIFLLTQLAVIA 725
             |.:|....  ||| ..|:|::   .:.....:.:|.|..|||
 Worm  1000 EDAHEVQMI--EEG-SICLNSVTVFAIFGTLAVLILGQTVVIA 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:459635	17/85 (20%)
		PAN_AP_HGF	211..285	CDD:238532	20/82 (24%)
		PAN_1	294..373	CDD:459635	25/143 (17%)
		ZP	381..615	CDD:214579	67/300 (22%)
noah-1	NP_740859.3	PAN_AP_HGF	107..189	CDD:238532
		PAN_AP_HGF	201..282	CDD:238532	6/23 (26%)
		PAN_AP_HGF	295..379	CDD:238532	21/96 (22%)
		PAN_AP_HGF	391..473	CDD:238532	20/86 (23%)
		PAN_APPLE	489..561	CDD:469620	14/82 (17%)
		ZP	731..933	CDD:214579	52/203 (26%)