DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and Matn4

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001239492.1	Gene:	Matn4 / 17183	MGIID:	1328314	Length:	624	Species:	Mus musculus

Alignment Length:	349	Identity:	69/349 - (19%)
Similarity:	118/349 - (33%)	Gaps:	114/349 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RRQAAE-SVTAAAPNASKVMASEEIKDK-----TEWPGAKETSTEINRT------ERPVENV--- 78
            ||:..| ::.|..|.|...|....|:..     :|..||:.:...:.|.      .||.:.|
Mouse    95 RREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEV 159

  Fly    79 --ETRNSGFDLPAASDLSSSLGSEEDSIYYDNAPVDCNPELV-GFEIVTGYVFSAPEKLMDSQPG 140
              :.|..|.::.|.....:.:||.....   :.|:|.:..|| .|:::..:......:|
Mouse   160 AAQARARGIEIYAVGVQRADVGSLRTMA---SPPLDQHVFLVESFDLIQEFGLQFQGRL------ 215

  Fly   141 TLMLTDCLDTCRKNKTCQSVNYETGLCVLFSAHADQLPGALTKSQFPVFTIYA-----------Q 194
                      |.|:...:.|:....|||       ..||          |.|.           .
Mouse   216 ----------CGKDLCAELVHGCQHLCV-------NAPG----------TFYCACNSGYKLAPDN 253

  Fly   195 KSCLAVKPCSRAWY------VDRVQNYKLKTEVKRTVSVASRRECFELCLGENDFTCRSANY-DR 252
            |:|||:..|:...:      |:.|.:|..:...             ...|.::..:||:.:| ..
Mouse   254 KNCLALDLCAEGTHGCEHLCVNSVDSYFCRCRA-------------GFALQQDQRSCRAIDYCSF 305

  Fly   253 TSGACELSELDRLTLAGSQAFQVNDGSDYL--------ENHCVDEPNKLCEFKRL---------- 299
            .:.:|:...:.  ||.|.|. :..:|.|.|        .:.|.|..:. |||:.:
Mouse   306 GNHSCQHECVS--TLEGPQC-RCREGHDLLPDGRSCRVRDFCNDVDHG-CEFQCVSEGLSFHCLC 366

  Fly   300 -PGRILKTVDSVYQEVSSIDECRE 322
             .||.|:.      :..|.|.|||
Mouse   367 PEGRRLQA------DGKSCDRCRE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	13/87 (15%)
		PAN_AP_HGF	211..285	CDD:238532	14/82 (17%)
		PAN_1	294..373	CDD:278453	11/40 (28%)
		ZP	381..615	CDD:214579
Matn4	NP_001239492.1	vWA_Matrilin	33..255	CDD:238752	36/195 (18%)
		FXa_inhibition	262..297	CDD:291342	5/47 (11%)
		FXa_inhibition	303..338	CDD:291342	8/37 (22%)
		FXa_inhibition	344..379	CDD:291342	8/41 (20%)
		vWA_Matrilin	385..621	CDD:238752	69/349 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000