DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and Matn1

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_034899.2	Gene:	Matn1 / 17180	MGIID:	106591	Length:	500	Species:	Mus musculus

Alignment Length:	360	Identity:	75/360 - (20%)
Similarity:	129/360 - (35%)	Gaps:	105/360 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 RTSG----ACELSELDRLTLAGSQAFQVNDGSDYLENHCVDEPNKLCEFKRLPGRILKTVDSVYQ 312
            |.||    |..:..:|:.||....:...::..||:|::.|.|            ::.|.....:.
Mouse   173 RASGIELFAIGVGRVDKATLRQIASEPQDEHVDYVESYNVIE------------KLAKKFQEAFC 225

  Fly   313 EVSSI-----DECRELCLNSP--YRC---HSYDYNDTGDM--VCRLSHHSRAT----LAD----V 357
            .||.:     .:|.:||::||  |.|   ..:..|..|..  |||......||    |.|    |
Mouse   226 VVSDLCATGDHDCEQLCVSSPGSYTCACHEGFTLNSDGKTCNVCRGGGSGSATDLVFLIDGSKSV 290

  Fly   358 QEPFLEVPEASTYELTSCYNVTIECGGGDMLARI----RTSKL--------FNGKVYAKGSPKSC 410
            :....|:.:....::....:|:      |.||::    .:|.:        |:.|...|.:.::.
Mouse   291 RPENFELVKKFINQIVDTLDVS------DRLAQVGLVQYSSSIRQEFPLGRFHTKKDIKAAVRNM 349

  Fly   411 SVDVK-----SALDFELRMNYHDLECNVRQS--------TAGR---YVNDIIIQHHDMIVTSSDL 459
            |...|     :||.: |..|...:....|..        |.||   |:||...:..|:......:
Mouse   350 SYMEKGTMTGAALKY-LIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAARKAKDLGFKMFAV 413

  Fly   460 GLALACQYDL---TNKSVSN----GVDLDVRGDIMPALSEEVIVESPNVIMRITSRDGSDMMRSA 517
            |:..|.:.:|   .::.|::    ..|......|...|.:::.||.
Mouse   414 GVGNAVEEELREIASEPVADHYFYTADFKTINQIGKKLQKQICVEE------------------- 459

  Fly   518 EVGDPLA----LKFEIVDEQSPYEIFIRELVAMDG 548
               ||.|    |||| ...:...:...|:|.|:.|
Mouse   460 ---DPCACESILKFE-AKVEGLLQALTRKLEAVSG 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532	10/36 (28%)
		PAN_1	294..373	CDD:278453	21/98 (21%)
		ZP	381..615	CDD:214579	41/207 (20%)
Matn1	NP_034899.2	vWA_Matrilin	42..265	CDD:238752	24/103 (23%)
Matn1	NP_034899.2	vWFA	276..499	CDD:294047	48/245 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000