DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-20

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_490798.1	Gene:	cutl-20 / 171678	WormBaseID:	WBGene00018787	Length:	360	Species:	Caenorhabditis elegans

Alignment Length:	374	Identity:	82/374 - (21%)
Similarity:	147/374 - (39%)	Gaps:	57/374 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   377 NVTIECGGGDMLARIRTSKLFNGKVYAK-GSPKSCSVDVKSALDFELRMNYHDLECNVRQSTAGR 440
            :.:|.|...|.|.:|:..:.|.|.:.:: |.||....:.....|.:.::......|:.:::..|.
Worm    25 DTSIACDKTDFLLKIKFDENFRGTIQSRAGHPKCIYANGTLQSDTKYQLKIPLTGCSTKENGEGN 89

  Fly   441 YVNDI-IIQHHDMIVTSSDLGLALAC--------QYDLTNKSVS-NGVDLDVRGDIMPALSEEVI 495
            ..|:| ::..::.....:|....|.|        :..:|   || .|:.::.......:||:...
Worm    90 LENEIEVVMANNEFNAETDKRFLLTCIPAAPVPKESQVT---VSFGGITINSDATTASSLSDNKT 151

  Fly   496 VESPNVIMRITSRDGSDMMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEITLIDSN 560
            |:....::...|.|...:.|...|||.:....|:.|:|:..   |....|.||:  ||:.|.||:
Worm   152 VDYRVRVLDGDSLDSKQLQRPLAVGDRVTYTVEMSDDQNGR---IGRCWANDGI--SELPLSDSH 211

  Fly   561 GC--PTDHFIMGPIYKGSVSGKMLLSN-FDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSG 622
            ||  .|...:.|.......:||.:..| ..|:.||:|..|.....:..|: :|....|.
Worm   212 GCSLQTSGEVWGDFEVTRRNGKTIFYNHIKAWAFPTSNEVNIFCNLHVCV-TCTQAACR------ 269

  Fly   623 EFRSLLSYGRKRRSLNTTDDHPRPRRD-----IDTSKKSAPSDMLLVQSIQITDKFGFKQDKQES 682
                    ||:||. |....|.....|     ||.|..|.|        |.:...|..   |:|:
Worm   270 --------GRERRH-NPPPQHSSTVSDPFSSTIDVSDISPP--------IAVRTSFRL---KREA 314

  Fly   683 GDFYDGNETTFTANEEGHGFCVNAIGLITAATIFLLTQLAVIAIWTYCY 731
            ....:.::||.:.:.:.   ..|:....::|.:..|..|.::|...:.|
Worm   315 VARLETSQTTSSVSTDS---STNSSSSSSSANLSFLFFLLIVASGVFDY 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	56/247 (23%)
cutl-20	NP_490798.1	Zona_pellucida	30..268	CDD:365872	56/246 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910