DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-13

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_490736.2	Gene:	cutl-13 / 171637	WormBaseID:	WBGene00021025	Length:	445	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	54/264 - (20%)
Similarity:	97/264 - (36%)	Gaps:	44/264 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 IECGGGDMLARIRTSKLFNGKVYAKG---SP---KSCSVDVKSALDFELRMNYHDLECNVRQST- 437
            ::|....:.....|...|.|.||.:|   :|   :......::...|.:|:.    :|.:|:|.
Worm    29 LQCNPESITFSFNTRNPFIGNVYIRGFYRTPGCRRQFLAPNQAGGSFTVRLG----DCGMRRSRQ 89

  Fly   438 ----AGRYVND---IIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVI 495
                :.|.||.   .:...|..:.|..:....:.|.|..:...|.  .||||..  ||   ||..
Worm    90 ISGHSPRGVNQHITFVANFHPNLATKEERSFNIRCFYAHSESVVK--ADLDVSS--MP---EESF 147

  Fly   496 VESPNVIMRIT--SRDGS---DMMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEIT 555
            .:...::.:.|  .|:|:   ..:.:..||..:..::: .|....|.|.:|....:|........
Worm   148 EQGVTIVPQCTYSLREGTFEGPKVSNTRVGMTIVHRWD-CDTSGNYGILLRGCTILDSRGVESFP 211

  Fly   556 LIDSNGCPTDHFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPC-----------MPS 609
            |:|.|||.........:|..|::...:.  .:|..||....:.|...:..|           .|:
Worm   212 LLDENGCSVSRDFPQVVYLPSLTSAYMA--IEAISFPDQPSISFSCQIKLCDKGSDECRGMSPPA 274

  Fly   610 CEPV 613
            |.|:
Worm   275 CTPL 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	54/263 (21%)
cutl-13	NP_490736.2	ZP	30..278	CDD:214579	53/261 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910