DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and AgaP_AGAP005350

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	XP_315362.4	Gene:	AgaP_AGAP005350 / 1276057	VectorBaseID:	AGAP005350	Length:	398	Species:	Anopheles gambiae

Alignment Length:	318	Identity:	77/318 - (24%)
Similarity:	132/318 - (41%)	Gaps:	73/318 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   404 KGSP-KSCSVDVKSALD-FELRM-NYHDLECNVRQSTAGRYVNDI----IIQHHDMIVTSSDLG- 460
            ||.| ..|...::..|. |||.: |.:|  |.|.     |.:|.|    :..|..::.|..|.|
Mosquito    23 KGYPDPKCKPTIRENLAVFELSLTNIYD--CGVT-----RVINQITGKKVFYHRIIVETGPDTGK 80

  Fly   461 --LALACQYDLTNKSVSNGVDLDVRGDIMPA---------LSEEVIVESPNVIMRITSRDGSDMM 514
              :::.|.....:.:|::|:   |:.|::||         ::..:...:|...:.|..|.| |.:
Mosquito    81 EIVSVKCITTGPSYNVTHGI---VKRDVLPAGFQEPEDLEITTSITENAPEPSLGIAIRQG-DKL 141

  Fly   515 RSAEV----GDPLALKFEIVDEQSP-YEIFIRELVAMDGVDNSEITLIDSNGCPTDHFIMGPIYK 574
            .|.::    |..|.::..:.:..:| |.:.:..::..| ....|.|:| .|||..|.::....
Mosquito   142 VSGDLNVSPGAHLQMEIFLDNRSAPIYGLGVNYMLVTD-TKYQEETII-FNGCSVDPYLFENF-- 202

  Fly   575 GSVSGKMLLSNFDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSGEFRSLLSYGRKRRSLNT 639
            .:|.|.:|.:.|.|||||.|..||||..|..|:..|:.|.|....|        ::||::|.::
Mosquito   203 NTVDGDLLAAKFRAFKFPESTYVQFRGTVNVCVDRCKGVICSNGQT--------AFGRRKREIS- 258

  Fly   640 TDDHPRPRRDIDTSKKSAPSDMLLVQSIQITDKFGFKQDKQESGDFYDGNETTFTANE 697
                            :||:|...|..:.:|......         ||.|....|.:|
Mosquito   259 ----------------AAPADPNKVYEVTMTTFIKVN---------YDENADQNTVSE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	62/234 (26%)
AgaP_AGAP005350	XP_315362.4	ZP	4..244	CDD:214579	62/235 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810