DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and AgaP_AGAP003211

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	XP_312919.4	Gene:	AgaP_AGAP003211 / 1273887	VectorBaseID:	AGAP003211	Length:	637	Species:	Anopheles gambiae

Alignment Length:	335	Identity:	78/335 - (23%)
Similarity:	138/335 - (41%)	Gaps:	57/335 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 PEASTYELTSCYNVTIECGGGDMLARIRTSKLFNGKVYAKG--SPKSCSVDVKS-----ALDFEL 422
            |.:::.:.....::.::|....|...|...:.|.|.:::||  |...| |.:|.     :..||:
Mosquito    85 PLSASNDSPQIKHLQVQCEKTHMRVNIEFDRPFYGMIFSKGFYSDPHC-VHLKPGTGHLSATFEI 148

  Fly   423 RMNYHDLECNVRQSTA--------GRYV-NDIIIQHHDMIVTSSDLGLALACQ-YDLTNKSVSNG 477
            .:|...:..:...:.|        |.|| |.||||:...:....|....|.|. ||...|:|:
Mosquito   149 FLNSCGMSSSANHNAASFGGPTPSGSYVENTIIIQYDPYVQEVWDQARKLRCTWYDFYEKAVT-- 211

  Fly   478 VDLDVRGDIMPALSEEVIVESPNVIMRITSRDG---SDMMRSAEVGDPLALKFEIVDEQSPYEIF 539
             ....:.|::.|::...:.::....|:|....|   |::....::|..:.:...|.|:::.:::.
Mosquito   212 -FRPFQVDMLHAVTANFLGDNLQCWMQIQVGKGPWASEVSGIVKIGQTMTMVLAIKDDENKFDML 275

  Fly   540 IRELVAMDGVDNSEITLIDSNGCPTDHFIMGPIYK----GSVSGKMLLSNFDAFKFPSSEVVQFR 600
            :|..||.|| ..:.|.|:|.:||.....||....|    |..:..:..:.|.|||||.|..|.|:
Mosquito   276 VRNCVAHDG-KRAPIQLVDQHGCVVRPKIMSKFQKIKNFGPSASVVSFAYFQAFKFPDSMNVHFQ 339

  Fly   601 ALVTPCMPSCEPVQCEQED----------TSGEFRS------------LLSYGRKRRSLNTTDDH 643
            .::..|..:|...:|...|          .|||:.:            |..||....:      :
Mosquito   340 CVIQVCRYNCPEPKCAGGDYGLPALTGNGISGEYGAPGPLSGEYGPPHLSEYGVPPAA------Y 398

  Fly   644 PRPRRDIDTS 653
            |.||...|.|
Mosquito   399 PDPRHPSDAS 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453	1/7 (14%)
		ZP	381..615	CDD:214579	64/257 (25%)
AgaP_AGAP003211	XP_312919.4	ZP	101..354	CDD:214579	64/257 (25%)
AgaP_AGAP003211	XP_312919.4	Zona_pellucida	<247..346	CDD:278526	27/99 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X161
TreeFam	0	0.000	Not matched by this tool.
	2	1.910