DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and AgaP_AGAP006705

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	XP_309038.2	Gene:	AgaP_AGAP006705 / 1270352	VectorBaseID:	AGAP006705	Length:	576	Species:	Anopheles gambiae

Alignment Length:	334	Identity:	73/334 - (21%)
Similarity:	123/334 - (36%)	Gaps:	63/334 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 TSCYNVTIECGGGDMLARIRTSKLFNGKVYAKG---SPKSCSVD--VKSALDFELRMNYHDLECN 432
            |...::..||....|..||..:..|||.:|:.|   .|....::  .:...:|.:::|
Mosquito   205 TRVQHIEAECQDDYMKIRIGFNGSFNGLLYSSGYAYDPDCMYINGSGRDYYEFFIQLN------- 262

  Fly   433 VRQSTAGRYV---------------NDIIIQHHDMIVTSSDLGLALACQ--YDLTNKSVSNGVDL 480
             |..|.|:..               |.:.:|::.:|....|....:.|:  ||.........:|:
Mosquito   263 -RCGTLGKNAIGEDSRKNPTKNFMWNTVTVQYNPLIEEEFDEHFKVTCEYGYDFWKTVTFPFLDV 326

  Fly   481 DVRGDIMPALSEEVI--VESPNVIMRITSRDGSDMMR---SAEVGDPLALKFEIVDEQSPYEIFI 540
            :|      |....|:  :..|...|.|.:..|::..|   ...|||||.|...:..:...::|.:
Mosquito   327 EV------ATGNPVVFTLSPPECYMEIRNGYGTNGARVTGPVRVGDPLTLIIYMRSKYDGFDIVV 385

  Fly   541 RELVAMDGVDNSEITLIDSNGCPTDHFIMGPIYKGS-----VSGKMLLSNFDAFKFPSSEVVQFR 600
            .:..|.:|. |..|.|||..|||.|..::.. ::||     |....:.:....|:|..|..:...
Mosquito   386 NDCFAHNGA-NKRIQLIDEYGCPVDDKLISR-FRGSWSDTGVFETQVYAYMKTFRFTGSPALYIE 448

  Fly   601 ALVTPCMPSCEPVQCEQEDTSG-------------EFRSLLSYGRKRRSLNTTDDHPRPRRDIDT 652
            ..|..|...|....|...:..|             .....:|..:..|.|...|:..|.:::..|
Mosquito   449 CDVRMCHGRCPSQPCHWRNLKGVTKREAVQPQVNTTLSDNISLFQALRVLQEEDEEARAKKESIT 513

  Fly   653 SKKSAPSDM 661
            |.|  |.||
Mosquito   514 SAK--PQDM 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453	73/334 (22%)
		ZP	381..615	CDD:214579	59/265 (22%)
AgaP_AGAP006705	XP_309038.2	ZP	213..464	CDD:214579	59/266 (22%)
AgaP_AGAP006705	XP_309038.2	Zona_pellucida	<362..463	CDD:278526	27/102 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910