DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and AgaP_AGAP007051

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	XP_308712.4	Gene:	AgaP_AGAP007051 / 1270050	VectorBaseID:	AGAP007051	Length:	433	Species:	Anopheles gambiae

Alignment Length:	425	Identity:	90/425 - (21%)
Similarity:	148/425 - (34%)	Gaps:	109/425 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 VTIECGGGDMLARIRTSKL-----FNGKVYAKGSPK--SCSVDVKSALDFELRMNYHDLE----- 430
            |.|:|..|.||..|:.:..     |:|.||.||..|  :|..:            ||:.|
Mosquito    41 VRIQCQSGSMLITIKDAPANLNGQFSGMVYPKGLAKNSTCLTE------------YHEQEGPLRY 93

  Fly   431 ------CN---VRQSTAG-RYVNDIIIQHHDMIVTSSDLGLALACQYDLTNKSVSN--------- 476
                  ||   :.....| .:.|.|::|.|..:||....|..:.|:|.....::.|
Mosquito    94 KLPLKSCNTMPIETEDGGIEFFNTIVLQPHLKLVTDLGRGYHVRCRYKSREAALKNVSYRHKAAD 158

  Fly   477 -------------GVDLDVRGDIMPALSEEVIVES------------PNVIMRITSRDGSDMMRS 516
                         |.|....|..|.:..::..|..            |...|:|.:  |..:..:
Mosquito   159 DSRPLALTSAEGAGPDRREHGRSMDSGKDDRAVSGEDGQQQDAGKPMPGCHMKIFT--GEKLAEN 221

  Fly   517 AEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEITLIDSNGCPTDHFIMGPIYKGSVSGKM 581
            .::||||.|...| |:|..|.:.:.:.:..||:...|..||...|||.|..|:||....:...|.
Mosquito   222 VKIGDPLTLVINI-DQQEEYGLHVTDCLVRDGLGWGEQKLISDEGCPLDSEILGPFEYTADRSKA 285

  Fly   582 LLSNFDAFKFPSSEVVQFRALVTPCM---PSCEPVQCEQEDTSGEFRSLLSYGRKRRSLNTTDDH 643
            .:: |.|.|||.:..|.::..|..|.   |.|.             ::.....:.||:...||:.
Mosquito   286 TVT-FPAHKFPYTSSVYYQCNVKLCALKDPDCH-------------KTPTCTNKSRRTKRQTDEE 336

  Fly   644 PRPRRDIDTSKKSAPSDMLLVQSIQITDKFGFKQDKQESGDFYDGNETTFTANEEGHGFCVNAIG 708
            .:|                  .:|::.......::.:...|..|......|.::   ..||:...
Mosquito   337 GQP------------------ATIEVFSGLHVNENAEVLSDDADSVLKEKTPDD---AICVSQRS 380

  Fly   709 LITAATIFLLTQLAVIAIWTYCYQRRQKLQPYQHS 743
            ...|..|..|..:..:.:...|...|:..:...||
Mosquito   381 FAVAIAIAGLCLMLAVVLAVMCIVARRSTKSVSHS 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	70/292 (24%)
AgaP_AGAP007051	XP_308712.4	ZP	44..323	CDD:214579	70/307 (23%)
AgaP_AGAP007051	XP_308712.4	Zona_pellucida	<221..323	CDD:278526	32/116 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910