Protein Alignment CG7829 and PRSS22

DIOPT Version :10

• Sequence 1: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 87/247 - (35%)
• Similarity: 132/247 - (53%)
• Gaps: 30/247 - (12%)

  Fly    27 RIVGGFPADIANIPYIVSIQLYGIHHCGGSIINNHTILTAGHCLN---GVPHRLLKVKVGG---- 84
            |:|||..:..:..|:|||||..|.|||.||::.:..::||.||..   ..|: |..|.:|.
Human   157 RVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPY-LFSVLLGAWQLG 220

  Fly    85 --TSRYRKDGELFSVADLQVHENFNPKT-MDYDIGIIRLTKNLTLSRKVKAI--PINPERVAEGT 144
              .||.:|.|    ||.::.|..::.|. ...||.::||.:::..|.:|..|  |.....:...|
Human   221 NPGSRSQKVG----VAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNT 281

  Fly   145 YATIAGWGFKSMNG---PPSDSLRYARVPIVNQTACRNLLGK-----TVTDRMLCAGYLKGGTDA 201
            :..|:||| ...:|   |...:|:..:|||::...|.:|..:     .:|:.|||||||:|..||
Human   282 HCWISGWG-SIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDA 345

  Fly   202 CQMDSGGPLSVREQ----LVGIVSWGVGCALADKPGVYSRLDALHPWLDQVL 249
            |..||||||..:..    |.||:|||.|||..::||||..|.|...|:::::
Human   346 CLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	86/240 (36%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	86/243 (35%)