DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7829 and PRSS1

DIOPT Version :9

Sequence 1:	NP_651732.1	Gene:	CG7829 / 43522	FlyBaseID:	FBgn0039703	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	244	Identity:	81/244 - (33%)
Similarity:	133/244 - (54%)	Gaps:	8/244 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLQASGCLSLESRPDPRIVGGFPADIANIPYIVSIQLYGIHHCGGSIINNHTILTAGHCLNGV 73
            |:|...:..|:.....|.:||||:..:..::||.||:. .|.|.||||:||...:::||||...
Human   230 LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKS- 292

  Fly    74 PHRLLKVKVGGTSRYRKDG--ELFSVADLQVHENFNPKTMDYDIGIIRLTKNLTLSRKVKAIPIN 136
               .::|::|..:....:|  :..:.|.:..|..::.||::.||.:|:|:....::.:|..|.:.
Human   293 ---RIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLP 354

  Fly   137 PERVAEGTYATIAGWGFKSMNGPP-SDSLRYARVPIVNQTACRNLLGKTVTDRMLCAGYLKGGTD 200
            ....|.||...|:|||..:.:|.. .|.|:....|:::|..|.......:|..|.|.|:|:||.|
Human   355 TAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKD 419

  Fly   201 ACQMDSGGPLSVREQLVGIVSWGVGCALADKPGVYSRLDALHPWLDQVL 249
            :||.|||||:....||.|:||||.|||..:|||||:::.....|:...:
Human   420 SCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	76/219 (35%)
CG7829	NP_651732.1	Tryp_SPc	28..248	CDD:238113	77/222 (35%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	76/220 (35%)
		Tryp_SPc	249..467	CDD:238113	77/222 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820