Protein Alignment CG7829 and PLAT

DIOPT Version :10

• Sequence 1: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 95/277 - (34%)
• Similarity: 141/277 - (50%)
• Gaps: 40/277 - (14%)

  Fly     4 KLWWKLL-LLQASGC-LSLESRPDPRIVGGFPADIANIPYIVSIQLYGIHH--------CGGSII 58
            :|.|:.. :...|.| |...|:|..||.||..||||:.|:..:|  :..|.        |||.:|
Human   285 RLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAI--FAKHRRSPGERFLCGGILI 347

  Fly    59 NNHTILTAGHCLNG--VPHRLLKVKVGGTSRYR----KDGELFSVADLQVHENFNPKTMDYDIGI 117
            ::..||:|.||...  .||. |.|.:|.|  ||    ::.:.|.|....||:.|:..|.|.||.:
Human   348 SSCWILSAAHCFQERFPPHH-LTVILGRT--YRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIAL 409

  Fly   118 IRLTKNLTL----SRKVKAIPINPE--RVAEGTYATIAGWGFKSMNGP-PSDSLRYARVPIVNQT 175
            ::|..:.:.    |..|:.:.:.|.  ::.:.|...::|:|......| .|:.|:.|.|.:...:
Human   410 LQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSS 474

  Fly   176 AC--RNLLGKTVTDRMLCAGYLKGG------TDACQMDSGGPL----SVREQLVGIVSWGVGCAL 228
            .|  ::||.:||||.|||||..:.|      .||||.||||||    ..|..||||:|||:||..
Human   475 RCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQ 539

  Fly   229 ADKPGVYSRLDALHPWL 245
            .|.||||:::.....|:
Human   540 KDVPGVYTKVTNYLDWI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	87/249 (35%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	2/10 (20%)
		Tryp_SPc	313..559	CDD:238113	86/249 (35%)