DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7829 and Prss53

DIOPT Version :9

Sequence 1:	NP_651732.1	Gene:	CG7829 / 43522	FlyBaseID:	FBgn0039703	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	68/292 - (23%)
Similarity:	112/292 - (38%)	Gaps:	76/292 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PDPRIVGGFPADIANIPYIVSIQLYGIHHCGGSIINNHTILTAGHCLNGVPHRLL---KVKVGGT 85
            |:|:.....|.:   .|:..|::..|:|.|.||::.:..:|||.||...:....|   .|.:|.
  Rat    36 PEPQEGNTLPGE---WPWQASVRRQGVHICSGSLVADTWVLTAAHCFEKMATAELSSWSVVLGS- 96

  Fly    86 SRYRKDG-----ELFSVADLQVHENFNPKTMDYDIGIIRLT-----KNLTLSRKVKAIPINPERV 140
              .:::|     |...||.||:.:.:|..:...|:.:::||     ..|.|.:.....|.
  Rat    97 --LKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHPIVHTTLCLPQPTHHFPF----- 154

  Fly   141 AEGTYATIAGWGFKSMNG-------------------------------------PPSDSLRYAR 168
              |......||...:.:|                                     |.|.:||..|
  Rat   155 --GASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLR 217

  Fly   169 VPIVNQTAC--------RNLLGKTVTDRMLCAGYLKGGTDACQMDSGGPLSVREQ-----LVGIV 220
            :.::::..|        :.||.......|||.|...|....||.|||||:..||.     .|||:
  Rat   218 LRLISRPTCNCLYNRLHQRLLANPARSGMLCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGII 282

  Fly   221 SWGVGCALADKPGVYSRLDALHPWLDQVLNKS 252
            |:...||..|.|.:.:.:.|...||...::::
  Rat   283 SFTSNCAQEDTPVLLTDMAAHSSWLQAHVDRA 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	64/279 (23%)
CG7829	NP_651732.1	Tryp_SPc	28..248	CDD:238113	66/282 (23%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	66/277 (24%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030