DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7829 and KLK12

DIOPT Version :9

Sequence 1:NP_651732.1 Gene:CG7829 / 43522 FlyBaseID:FBgn0039703 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_062544.1 Gene:KLK12 / 43849 HGNCID:6360 Length:254 Species:Homo sapiens


Alignment Length:230 Identity:70/230 - (30%)
Similarity:107/230 - (46%) Gaps:20/230 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 LSLESRPDPRIVGGFPADIANIPYIVSIQLYGIHHCGGSIINNHTILTAGHCLNG------VPHR 76
            |.|.....|:|..|......:.|:.|.:.......|||.:|::..:|||.||...      ..|.
Human    12 LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHS 76

  Fly    77 LLKVKVGGTSRYRKDGELFSVADLQVHENF--NPKTMDYDIGIIRLTKNLTLSRKVKAIPINPER 139
            |  .::..|.:.|..|  |||    .|..:  ...:.::|:.::||...:.::..|:.:|:..:.
Human    77 L--SQLDWTEQIRHSG--FSV----THPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDC 133

  Fly   140 VAEGTYATIAGWGFKS-MNGPPSDSLRYARVPIVNQTACRNLLGKTVTDRMLCAGYLKGGTDACQ 203
            ...||...::|||..: ...|..|.|:...:.||:...|..:....:|..|:|||.:. |.||||
Human   134 ATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQ 197

  Fly   204 MDSGGPLSVREQLVGIVSWG-VG-CALADKPGVYS 236
            .||||||.....|.|:|||| || |.....||||:
Human   198 GDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7829NP_651732.1 Tryp_SPc 27..244 CDD:214473 67/221 (30%)
Tryp_SPc 28..248 CDD:238113 67/220 (30%)
KLK12NP_062544.1 Tryp_SPc 21..236 CDD:214473 67/221 (30%)
Tryp_SPc 22..236 CDD:238113 67/220 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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