Protein Alignment CG7829 and KLK2

DIOPT Version :10

• Sequence 1: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 77/264 - (29%)
• Similarity: 127/264 - (48%)
• Gaps: 29/264 - (10%)

  Fly     7 WKLLLLQA--SGCLSLESRPDPRIVGGFPADIANIPYIVSIQLYGIHHCGGSIINNHTILTAGHC 69
            |.|:|..|  .||.........|||||:..:..:.|:.|::..:|..||||.:::...:|||.||
Human     2 WDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC 66

  Fly    70 LNGVPHRLLKVKVGGTSRYRKD--GELFSVA----------DLQVHENFNP-KTMDYDIGIIRLT 121
            |.    :..:|.:|..:.:..:  |:...|:          .|..|::..| :...:|:.::||:
Human    67 LK----KNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127

  Fly   122 KNLTLSRKVKAIPINPERVAEGTYATIAGWGFKSMNGPPSD-----SLRYARVPIVNQTACRNLL 181
            :...::..||.:.:..:..|.||....:|||    :..|.:     ||:...:.:::...|....
Human   128 EPAKITDVVKVLGLPTQEPALGTTCYASGWG----SIEPEEFLRPRSLQCVSLHLLSNDMCARAY 188

  Fly   182 GKTVTDRMLCAGYLKGGTDACQMDSGGPLSVREQLVGIVSWG-VGCALADKPGVYSRLDALHPWL 245
            .:.||:.|||||...||.|.|..||||||.....|.||.||| ..|||.:||.||:::.....|:
Human   189 SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253

  Fly   246 DQVL 249
            ...:
Human   254 KDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	70/235 (30%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	70/238 (29%)