Protein Alignment CG7829 and spirit

DIOPT Version :10

• Sequence 1: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 1215
• Identity: 227/1215 - (18%)
• Similarity: 382/1215 - (31%)
• Gaps: 438/1215 - (36%)

  Fly   238 SFFSSSSPCLL----RLIQKILEE---IAKLPELLNHSGLPLRPEEHLPYFDPKKYEQLLATAVL 295
            :|.|::..|:.    .||.|::..   :.|:......:.|.|:||.      .:.:.::|:..:.
  Fly    93 TFGSATEYCMCFVMPNLIPKLVSNKVTVRKITHQAIATFLRLKPEA------LQSFLKMLSNFMP 151

  Fly   296 NKVSAGPCRLAFERVMQLAGRLVCLHVSGRATPIYPNIETES----ADDQAPQPHEGVSYSAIGT 356
            |      |....|.:.:|...|:...|....|.:..|..|||    .:|||....:.:.| .||.
  Fly   152 N------CNSKSELITELHHILIPELVKSNWTCLVENFTTESNIQGCEDQAGVLMKKLHY-FIGN 209

  Fly   357 E------RRLSDTDESYLSDYIQRHKVPLPDLSDTTGSG---------SGAE--------DDDLQ 398
            |      ..||......|.....  .|.:.......|||         ||.|        ...:.
  Fly   210 EFWQKIITNLSPEKREVLEQITA--NVQVEHTESKAGSGVLRASAKPQSGGERRLRFGIVPSLVC 272

  Fly   399 SLKSNATDGTWEENWLFRKRQL--KTTESSIAMLVP---SPTEEVKALIGDKNADEI---SDLSE 455
            :|.:..||.....:.|.:.:|:  :.|...||.|||   |....:..::.|.|...:   .|:..
  Fly   273 ALIAEDTDANQRISGLEKMKQVVDQITPEEIARLVPHLHSYLLMLSNVLEDLNFKVVVLALDIVR 337

  Fly   456 A-GSDCEGY--------------------------------ESDGNVNGGTVPSVAPVVVASSSK 487
            | |...:|:                                |...|:|..||.....|.:.:.:.
  Fly   338 ATGHHLKGHMEAHIQQFVNLVAKHFGNQKSVIKQIIMMTFMELFQNINPKTVGGCLRVFLENKNS 402

  Fly   488 DTTSEGIS---------SSSK--TQSLDEILPP------------------------DSLVSINS 517
            ....|.|:         |.||  .|.|..||.|                        :....|..
  Fly   403 RVREEVINIYTASLMTISPSKFNLQPLVNILVPMFHDVKKRVRLAAFEQLSVLAYLLNGKTEIIM 467

  Fly   518 LPV-------NEEALSEATNSQLLADQVAQNGASERLQVDDLISIEPVADRVETTNPTLTNPFLD 575
            .||       |...|:||..:::      :.....|::.|.||         |.:.|.:.:.|
  Fly   468 KPVRDFEQDQNSRGLTEAVTARI------RRQVLPRIRYDGLI---------EYSTPPMMDSF-- 515

  Fly   576 DVFEANNNVITDDVKMLQRTETGDNRSSATESNGYGDRKEIPIDRAQIATNGGDVPEVQGDSGEQ 640
            |:.||..::                     .||.         |.:.|.:|||    |:.|..|:
  Fly   516 DLAEAEMSL---------------------PSNA---------DLSWIVSNGG----VEPDPFER 546

  Fly   641 DASVDAPDTLIPGSIAEREHLKWRN---------AKPIANNPYSP-----DVLQR-----RLSEK 686
                    |:.|.|:|.......||         .||..:.|..|     ...||     ..|.:
  Fly   547 --------TMSPISLAGNLATIRRNRVIQQQGQAEKPSFSLPQQPAQQASHQAQRLPNGIEKSHE 603

  Fly   687 TRPSSMIEI------------DRLVRKEAAPATGGAAGGVLIDDEETPKEPTDSGTENDRSLQSV 739
            |..:|.::|            |..||::.:.|:...:.   ....|.||.|..|.:|...
  Fly   604 TSENSSLDIGQRIVMTRMKSDDSFVRRQGSAASNPNSS---TSSWEAPKRPPISPSEKSS----- 660

  Fly   740 TGGVLTETKKIGREYYINDPERLRAGGAPLKSTL----GPQTQTQQPSHSTDDEKVSHQTYYTLP 800
                ::.|||.....:|.....|::..|...:.|    |.:.....|..|.||........|:.
  Fly   661 ----ISATKKEVNNNHIVKKGNLKSMRARSDTNLSEDHGEEEMENDPPRSFDDRPAKASGQYSF- 720

  Fly   801 ADSYLMDRFLNNATAPATVGRSASIRSIRSLP-------QHELA------NGSGSVHRAASVDLG 852
                   :..:.|..|:::|:.:.  |..|||       :|.::      |.:|:..|:..   |
  Fly   721 -------QDFDAAIVPSSMGKKSI--SHHSLPITSHPPLKHAISQPQKRINNNGTFLRSGQ---G 773

  Fly   853 YQTKTPS------AAGSDTAPAVDIPAHILAQFEQETLHSDYKRDSFRARHATTRQFVLNPIFDE 911
            .:||:.|      .|.|.|...:|                             |....:|....:
  Fly   774 QRTKSVSKPHRELTAVSKTYSLLD-----------------------------TSNMSVNQALKK 809

  Fly   912 QSS-PGPDQTDG---AERAAHTLPR------KARVAAAAGGRGIVPEPVKPGRGQVVETVFTDLG 966
            .|| ...|:.||   ....:.|.||      |..:.|       :....|..|..|.......:|
  Fly   810 MSSDEWADKVDGLNMISTLSETQPRMVADNLKEVIIA-------ILNECKNLRSSVSRVAIVTIG 867

  Fly   967 TLRRSASS-----------LLLGRAVDESEAAAPQKLTPEPVSSLYRSSSVGKQRDPRAEDIFAA 1020
            |:.::.:|           :||.::.|.|.|......| :.::.|.::::.||
  Fly   868 TVAQNLNSKIDSEMEKICAVLLSKSGDVSNAFIRDDAT-DSLNKLVKAATAGK------------ 919

  Fly  1021 RPVQVTADDPILQQGTKV---SYLSTAAREIY-LVPVESEPNGGSLMSSSSELSSVHSPTNAHQR 1081
                  |...|:..|.|.   :..|:.|..:| ::.::   ...:::::.:.||:|        .
  Fly   920 ------ALQGIILAGAKSKNNTIRSSCANFVYDIITIQ---GSSAILNNQNALSNV--------L 967

  Fly  1082 PELDSLTYSEDSDVTRIYDLTTGEAKVVRTCHSETEPPHDTILQILPQ-PSPTKQQPAMMATAPS 1145
            |.|  |.:|.|..                                 || .:|.||....::..|:
  Fly   968 PVL--LQFSRDQS---------------------------------PQVRNPGKQSLCFLSKDPN 997

  Fly  1146 HE----QSSSSSNVSALKSQLSTGERADAGSYHRRSPFPVKPLSPETIKFFAPKRKLSFTGSTNS 1206
            .:    :::..|.:.|:|..|:..|:                                 .|..:|
  Fly   998 FDRLMRKNALESEIKAVKDVLANVEK---------------------------------RGGVDS 1029

  Fly  1207 LVGESGSKGAGSEQGTT-HVLPSMHSSLHIDYPASRS---ATGSE 1247
            |...:...|:.|..|:| .|...:..||.:|....|:   |.|.|
  Fly  1030 LESTANLSGSLSRIGSTRRVQKKLPDSLQLDLDEIRTELLAAGWE 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	2/5 (40%)
spirit	NP_572492.1	CLIP	51..98	CDD:197829	2/4 (50%)
		Tryp_SPc	132..364	CDD:238113	51/246 (21%)