DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7829 and svh-1

DIOPT Version :9

Sequence 1:	NP_651732.1	Gene:	CG7829 / 43522	FlyBaseID:	FBgn0039703	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	74/243 - (30%)
Similarity:	122/243 - (50%)	Gaps:	26/243 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RIVGGFPADIANIPYIVSI--QLYGIHHCGGSIINNHTILTAGHCLNGVPHRL--LKVKVGGTSR 87
            |:||||.......|:..::  :....||||.||::...::||.||.. ...|:  .:|.||....
Worm   712 RVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFE-EDERVSSYEVVVGDWDN 775

  Fly    88 YRKDG--ELFSVADLQVHENFNPKTMD---YDIGIIRLT-KNLTLSRKVKAI--PINPERVAEGT 144
            .:.||  ::|.:.  ::|  |.|...|   :||.|:.:. ..:..:...:.|  |........|.
Worm   776 NQTDGNEQIFYLQ--RIH--FYPLYKDIFSHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGR 836

  Fly   145 YATIAGWGFKSMNGPPSDSLRYARVPIVNQTACRN--LLGKTVTDRMLCAGYLKGGTDACQMDSG 207
            ...::|||  ||....::.|:.|.:||:|:..|.|  .:..:::....|||||:||.|:||.|||
Worm   837 QCVVSGWG--SMGLRYAERLQAALIPIINRFDCVNSSQIYSSMSRSAFCAGYLEGGIDSCQGDSG 899

  Fly   208 GPLSVREQ-----LVGIVSWGVGCALADKPGVYSRLDALHPWLDQVLN 250
            ||.:.|.:     |.|::|||.|||...:||:|:.:.....|:..::|
Worm   900 GPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISAIIN 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	72/235 (31%)
CG7829	NP_651732.1	Tryp_SPc	28..248	CDD:238113	72/238 (30%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	72/238 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910