Protein Alignment CG7829 and KLK8

DIOPT Version :10

• Sequence 1: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 87/303 - (28%)
• Similarity: 127/303 - (41%)
• Gaps: 68/303 - (22%)

  Fly     4 KLWWKLLLL----QASGCLSL-----------------------------ESRPDP--------- 26
            |.|..||||    .|.|.|.|                             .|.|.|
Human    10 KTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWRSNPLPPAAGHSRAQ 74

  Fly    27 --RIVGGFPADIANIPYIVSI----QLYGIHHCGGSIINNHTILTAGHCLNGVPHRLLKVKVGGT 85
              :::||......:.|:..::    ||.    |||.::..:.:|||.||..  |.  ..|::|..
Human    75 EDKVLGGHECQPHSQPWQAALFQGQQLL----CGGVLVGGNWVLTAAHCKK--PK--YTVRLGDH 131

  Fly    86 SRYRKDGELFSVADLQ--VHENFNPKTMD---YDIGIIRLTKNLTLSRKVKAIPINPERVAEGTY 145
            |...|||....:..:|  .|..:|...::   :|:.:::|....:|..|||.|.:.......|..
Human   132 SLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK 196

  Fly   146 ATIAGWGFKSMNGPPS---DSLRYARVPIVNQTACRNLLGKTVTDRMLCAGYLKGGTDACQMDSG 207
            .|::|||  ::..|..   |:|..|.|.|..|..|.:.....:||.|:|||..| |.|.||.|||
Human   197 CTVSGWG--TVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK-GADTCQGDSG 258

  Fly   208 GPLSVREQLVGIVSWGVG-CALADKPGVYSRLDALHPWLDQVL 249
            |||.....|.||.|||.. |..:||||||:.:.....|:.:::
Human   259 GPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	73/229 (32%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	73/230 (32%)