DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ca and AT1G69710

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_177129.2	Gene:	AT1G69710 / 843307	AraportID:	AT1G69710	Length:	1041	Species:	Arabidopsis thaliana

Alignment Length:	772	Identity:	171/772 - (22%)
Similarity:	270/772 - (34%)	Gaps:	240/772 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1041 PFSPALRPIVSHNSDCAMSNDNNPQLFEFCKSLIETYLAVLIHMESQRVKYDSIVNALSNFRINY 1105
            ||||.  |....||:...|. |:|                      .|:...|.|:..|:.  :|
plant   215 PFSPT--PANVENSNLRFST-NDP----------------------FRLSLSSAVSTSSHG--SY 252

  Fly  1106 EDNQFAIESSRFKPISAGCAYCACVVDGTAYFWG---SSGIPSYYSAQKSTEPPEPAHAVKSLDL 1167
            .::..|:                    |..:.||   |.|:.| .:........|.|...|:|:
plant   253 HEDFDAL--------------------GDVFVWGESISDGVLS-GTGNSLNSTTEDALLPKALE- 295

  Fly  1168 LSQLNLQVHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLE 1231
             |.:.|....|.||:.|.:::|..| ::|.|.....:||.|.... |.:|..::::.|:....|.
plant   296 -STIVLDAQNIACGKCHAVLVTKQGEIFSWGEGKGGKLGHGLETD-AQKPKFISSVRGLGFKSLA 358

  Fly  1232 AGQYHNAAVA-DGKLYMWGWGIYG--QLGQGSCENIATPQLVS-FFKFKKILQISLGHAHTLVLC 1292
            .|.:|..|:. .|.||.||.|.:.  .||.|:..:...|:.|: ..:...:..::.|..||.|:.
plant   359 CGDFHTCAITQSGDLYSWGDGTHNVDLLGHGNESSCWIPKRVTGDLQGLYVSDVACGPWHTAVVA 423

  Fly  1293 GAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTK-TNLPVRLE--VGDCSLRLIHTKF--- 1351
            .:           .:||.||...||.||     |||.: |::|..:|  :|     ||.||.
plant   424 SS-----------GQLFTFGDGTFGALG-----HGDRRSTSVPREVESLIG-----LIVTKVACG 467

  Fly  1352 ---------FTNLA----VD-EQDRLFTWGSSPQALRLANQIKRRANAKQKMEENQQRELLSKQL 1402
                     .||.|    || .:.::||||                       :.::.:|.....
plant   468 VWHTAAVVEVTNEASEAEVDSSRGQVFTWG-----------------------DGEKGQLGHGDN 509

  Fly  1403 EATLLPAPIPST------------STLVEPTTSYAAVVAGSTPKSSVSDTKDCQDVQNEAAPSDA 1455
            :..|||..:.|.            |..|..|:.......|||                      |
plant   510 DTKLLPECVISLTNENICQVACGHSLTVSRTSRGHVYTMGST----------------------A 552

  Fly  1456 TETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLTPHLVDTSEVAGRILQISSGLFHFCLISSSC 1520
            ...:...:||...|                 |.:...:|:.|     :.:|:.|.:|..:::|..
plant   553 YGQLGNPTAKGNFP-----------------ERVEGDIVEAS-----VEEIACGSYHVAVLTSKS 595

  Fly  1521 TLYTWGKNLEHQLG---TEDKDRRAV---LKPSPIDSIERPMYVDCGSDFTLVMTTDHVVRAFGG 1579
            .:|||||.|..|||   .|:|...||   |:...:.:|      .|||:||.|:.   |.:...|
plant   596 EIYTWGKGLNGQLGHGNVENKREPAVVGFLREKQVKAI------TCGSNFTAVIC---VHKWVPG 651

  Fly  1580 NSNGQCGRDLGPSVERMRQRVVCLPATKRLVRFESQCVEVPVEINLPRPRIRLDQDPVRYLKVMP 1644
            :.:..|.....|...| |:|..|.           .|..|..::...|..:|....|    .:..
plant   652 SEHSLCAGCRNPFNFR-RKRHNCY-----------NCGLVFCKVCSSRKSLRAALAP----DMNK 700

  Fly  1645 PYQPHFLQPANISFDQHCSVGTP--------NYKSSTEHAATGQDSDDMLSSLENLSQNDASFSY 1701
            ||:..:.....:...:..|..||        |.:.||:.:.....:...||....||..|:|..|
plant   701 PYRVCYGCFTKLKKSRESSPSTPTSRTRKLLNMRKSTDVSERDSLTQKFLSVNARLSSADSSLHY 765

  Fly  1702 ---------------NAPVLGDAHSSLDMDYTPEEQSYVPLPE-------QAVGSGM 1736
                           |:.|....:.||....:|..:....||:       :..||||
plant   766 SERRHHRRDLKPEVNNSNVFPSMNGSLQPVGSPFSKGSTALPKIPKNMMVKIPGSGM 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	112/472 (24%)
		RCC1_2	1175..1200	CDD:290274	8/25 (32%)
		RCC1	1193..1240	CDD:278826	11/46 (24%)
		RCC1	1242..1291	CDD:278826	14/51 (27%)
		RCC1_2	1503..1532	CDD:290274	10/28 (36%)
		RCC1	1522..1568	CDD:278826	20/51 (39%)
		RCC1_2	1558..1584	CDD:290274	8/25 (32%)
AT1G69710	NP_177129.2	PH_PLC_plant-like	25..135	CDD:270171
		RCC1_2	354..381	CDD:290274	10/26 (38%)
		RCC1	370..422	CDD:278826	14/51 (27%)
		RCC1	425..474	CDD:278826	19/69 (28%)
		RCC1	491..537	CDD:278826	10/68 (15%)
		RCC1	543..591	CDD:278826	13/91 (14%)
		RCC1	596..643	CDD:278826	20/52 (38%)
		FYVE	646..714	CDD:214499	14/83 (17%)
		DUF4200	838..936	CDD:290574
		BRX_N	896..>921	CDD:290432
		BRX	981..1035	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820