DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ca and AT3G23270

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001327882.1	Gene:	AT3G23270 / 821906	AraportID:	AT3G23270	Length:	1054	Species:	Arabidopsis thaliana

Alignment Length:	1022	Identity:	211/1022 - (20%)
Similarity:	336/1022 - (32%)	Gaps:	304/1022 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1042 FSPALRPIVSHNSDCAMSNDNNPQLFEFCKSLIET---YLAVLIHMESQRVK---------YDS- 1093
            |...|||...|.|...:.|:....|...||...||   :.|:...:|..|.:         :||
plant    79 FKRFLRPEKDHLSFSLLYNNRERSLDLICKDKAETEVWFAALKFLIEKSRNRRARSEIPEIHDSD 143

  Fly  1094 ---------------IVNALSNFRINYEDNQ----------------FAIESSRFKPISAGCAYC 1127
                           |....::..:.|::|.                |.|..|.....|:|.:..
plant   144 TFSVGRQSIDFVPSNIPRGRTSIDLGYQNNSDVGYERGNMLRPSTDGFRISVSSTPSCSSGGSGP 208

  Fly  1128 ACVVD-GTAYFWGS--------SGIPSYYSAQKSTEPPEPAHAVKSLDLLSQLNLQVHAIKCGRQ 1183
            ..:.. |..|.||.        .|..|..:.:.....|.|        |.|.:.|.||.|.||.:
plant   209 DDIESLGDVYVWGEVWTEGILPDGTASNETVKTDVLTPRP--------LESNVVLDVHQIVCGVR 265

  Fly  1184 HTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYHNAAVA-DGKLY 1246
            |..::|..| :::.|.....:||.|..:.:: :|.||..|...||..:..|:||...|: .|.|:
plant   266 HVALVTRQGEVFTWGEEVGGRLGHGIQVDIS-RPKLVEFLALTNIDFVACGEYHTCVVSTSGDLF 329

  Fly  1247 MWGWGIY--GQLGQGSCENIATPQLVSF-FKFKKILQISLGHAHTLVLCGAPNSHMEANHCGNEL 1308
            .||.||:  |.||.||..:...|:.||. .:..::|.::.|..|:.:        ..||   .:|
plant   330 SWGDGIHNVGLLGHGSDISHWIPKRVSGPLEGLQVLSVACGTWHSAL--------ATAN---GKL 383

  Fly  1309 FVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGD--------CSLRLIHTKFFTNL----AVDEQD 1361
            |.||...||.||.||.:    ..:.|..::..:        ||  :.||.....:    |.....
plant   384 FTFGDGAFGVLGHGNRE----SVSYPKEVQSLNGLKTVKVACS--IWHTAAIVEVMGQTATSMSS 442

  Fly  1362 R-LFTWGSSPQALRLANQIKRRANAKQKMEENQQRELLSKQLEATLLPAPIPS------------ 1413
            | |||||...         |.|.....|              |..|||..:.|
plant   443 RKLFTWGDGD---------KNRLGHGNK--------------ETYLLPTCVSSLIDYNFHKIACG 484

  Fly  1414 -TSTLVEPTTSYAAVVAGSTP---KSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVA 1474
             |.|:...|:.:...:.|:..   .:|:||.|
plant   485 HTFTVALTTSGHVFTMGGTAHGQLGNSISDGK--------------------------------- 516

  Fly  1475 SPPVLVPEPDPTEHLTPHLVDTSEVAGRILQISSGLFHFCLISSSCTLYTWGKNLEHQLG---TE 1536
                           .|.||....|...:.:|:.|..|..:::|...::||||....:||   ||
plant   517 ---------------LPCLVQDRLVGEFVEEIACGAHHVAVLTSRSEVFTWGKGANGRLGHGDTE 566

  Fly  1537 DKDRRAVLKPSPIDSIERPMYV---DCGSDFT-------LVMTTDHVV-----RAFG----GNSN 1582
            ||     ..|:.:::: |..:|   .|||:||       .|...|..:     :|||    .::.
plant   567 DK-----RTPTLVEAL-RDRHVKSLSCGSNFTSSICIHKWVSGADQSICSGCRQAFGFTRKRHNC 625

  Fly  1583 GQCG--------------RDLGPSVERMRQRVVCLPATKRLVRFESQCVEVPVEINLPRP----- 1628
            ..||              ..|.|:..:..:  ||.....:|...||. ....|..|:..|
plant   626 YNCGLVHCHACSSKKALKAALAPTPGKPHR--VCDACYSKLKAAESG-YSSNVNRNVATPGRSID 687

  Fly  1629 -RIRLDQDPVRYLKVMPPYQPHFLQPANISFDQHCSVGTPNYKSSTEHAATGQDSDDMLSSLENL 1692
             .:|.|::..|..||:                  .|....:..||:....|.:.|:...|.:.:|
plant   688 GSVRTDRETTRSSKVL------------------LSANKNSVMSSSRPGFTPESSNARASQVPSL 734

  Fly  1693 SQ-NDASFSYNAPVLGDAHSSLDMDYTPEEQSYVPLPEQAVGSGMPANAEQLLGRDDDDGSTYTQ 1756
            .| .|.:|..:...:.:|...:....|...::.|..|........|.::.....|..      ..
plant   735 QQLKDIAFPSSLSAIQNAFKPVVAPTTTPPRTLVIGPSSPSPPPPPRSSSPYARRPS------PP 793

  Fly  1757 STEGMGESSLQHLRHYIHYCLYAFHGLYNPDKIGECARPHRNEYRIRICMLNFRFVEAFRLCLQS 1821
            .|.|...|.:..||                 |..|.......:...::..|.           |.
plant   794 RTSGFSRSVIDSLR-----------------KTNEVMNQEMTKLHSQVKNLK-----------QR 830

  Fly  1822 CGSAQRTLKLFEYFSKDTGYVPLRRTDLKHLIYHLCLHFLERKFDMLECERFFMGDLDYYLLELA 1886
            |.:....::.|:..:||...:..|::. ||......|..:..:...|:         :....|::
plant   831 CNNQGTEIERFQKAAKDASELAARQSS-KHKAATEALKSVAEQLKELK---------EKLPPEVS 885

  Fly  1887 YVFYFNNNNSTLEQNLNQKFKQLIAAADSNQAATSAGQELEQLQDTD 1933
            ....|.:.||..|..||..      ........|::|||.|..|.|:
plant   886 ESEAFESINSQAEAYLNAN------KVSETSPLTTSGQEQETYQKTE 926

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	116/499 (23%)
		RCC1_2	1175..1200	CDD:290274	9/25 (36%)
		RCC1	1193..1240	CDD:278826	13/46 (28%)
		RCC1	1242..1291	CDD:278826	17/51 (33%)
		RCC1_2	1503..1532	CDD:290274	8/28 (29%)
		RCC1	1522..1568	CDD:278826	18/58 (31%)
		RCC1_2	1558..1584	CDD:290274	11/44 (25%)
AT3G23270	NP_001327882.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820