DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ca and AT3G03790

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001189802.1	Gene:	AT3G03790 / 821145	AraportID:	AT3G03790	Length:	1099	Species:	Arabidopsis thaliana

Alignment Length:	731	Identity:	140/731 - (19%)
Similarity:	239/731 - (32%)	Gaps:	300/731 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly  1165 LDLLSQLNLQVHAIKCGRQHTLILTNNGLYSLGNNNLCQLGIG-RHMQMALQPMLVTALDGMNIT 1228
            :||:|....||    .|.|.:.:.|.  ::|.||....|||.| :|:|..  |..|.:|.|..|.
plant   133 VDLVSGPVAQV----IGEQQSSVATE--VFSWGNGANYQLGTGNQHVQKV--PGRVDSLHGCFIK 189

  Fly  1229 MLEAGQYHNAAVA-DGKLYMWGWG----------------------------------------- 1251
            ::.|.::|:.|:: .|::|.||:|
plant   190 LVSAAKFHSVAISTHGEVYTWGFGRGGRLGHPEFDIHSGQAAVITPRQVISGLGSRRVKAVAAAK 254

  Fly  1252 -----------IY-------GQLGQGSCENIATPQLVSFFKFKKILQISLGHAHTLVLCGAPNSH 1298
                       :|       ||||..|.:..|||:.|:..| .||:.:|..:.||.|:
plant   255 HHTVIATEGGDVYTWGSNREGQLGYTSVDTQATPRKVTSLK-AKIVAVSAANKHTAVV------- 311

  Fly  1299 MEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGDCSLRLIHTKFFTNLAVDEQDRL 1363
               :.|| |:|.:|.|..||||.|.|:.....:...|....|.....:..:|:.| |.:.....:
plant   312 ---SDCG-EVFTWGCNKEGQLGYGTSNSASNYSPRLVDYLKGKVFTAIASSKYHT-LVLRNDGEV 371

  Fly  1364 FTWGS---SPQALRLANQIKRRANAKQKMEENQQRELLSKQLEATLLPAPIPSTSTLVEPTTSYA 1425
            :|||.   :|:.:.::..:|:..|........       :.|..|.:.|.:..:..|.|....:.
plant   372 YTWGHRLVTPRRVIISRNLKKAGNTLLNFHRR-------RPLRLTAIAAGMVHSLALAEDGAFFY 429

  Fly  1426 AVVAGSTPKSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLT 1490
            .|       ||.|:.: ||.:.:
plant   430 WV-------SSDSNLR-CQQLHS------------------------------------------ 444

  Fly  1491 PHLVDTSEVAGR-ILQISSGLFHFCLISSSCTLYTW-GKNLEHQLGTEDKDRRAVLKPSPIDSIE 1553
                    :.|: ::.||:|.:....::|:..:|.| |||
plant   445 --------LHGKTVVSISAGKYWASAVTSTGEVYMWDGKN------------------------- 476

  Fly  1554 RPMYVDCGSDFTLVMTTDHVVRAFGGNSNGQCGRDLGPSVERM----RQRVVCL----------- 1603
                                            |:|:.||:.|:    |...|.:
plant   477 --------------------------------GKDIAPSLSRLHNLKRATTVAVGETHLLVVGSL 509

  Fly  1604 --PATKRLVRFESQ------CVEVPVEINLPRPRIRLDQ----DPVRYLKVMPPYQPHFLQPANI 1656
              ||...:|..:||      |.|...|        .||:    |.|..:.|:          .::
plant   510 YHPAYAPIVLKKSQTLQADKCREEENE--------ELDEGFMFDDVESVNVL----------QSV 556

  Fly  1657 SFDQHCSVGTPNYKSSTEHAAT-----GQDSDDMLSSLENLSQNDASFSYNAPVLGDAHSSLD-- 1714
            .:|.......|:.||..|..|.     .:::..:|...::|...|........|:    .:||
plant   557 QYDNPKERIVPSLKSLCEKVAAECIVEPRNAIQLLEIADSLGAEDLKKYCEDIVI----RNLDFI 617

  Fly  1715 MDYTPEEQSYVPLPEQAVGSGMP---ANAEQLLGRDDDDGSTYT---------------QSTEGM 1761
            :.::|          |::.:..|   ||.|:||  ||....|::               .|.|..
plant   618 LTFSP----------QSIANTSPDVLANLEKLL--DDRSSETWSSRPLPTPTATFPVVIDSEEEE 670

  Fly  1762 GESSL-----QHLRHY 1772
            .||.:     .|::|:
plant   671 SESDILRTRDSHVKHF 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	92/488 (19%)
		RCC1_2	1175..1200	CDD:290274	7/24 (29%)
		RCC1	1193..1240	CDD:278826	16/47 (34%)
		RCC1	1242..1291	CDD:278826	21/107 (20%)
		RCC1_2	1503..1532	CDD:290274	9/29 (31%)
		RCC1	1522..1568	CDD:278826	5/46 (11%)
		RCC1_2	1558..1584	CDD:290274	0/25 (0%)
AT3G03790	NP_001189802.1	ANK	29..137	CDD:238125	2/3 (67%)
		Ank_2	29..126	CDD:289560
		ANK repeat	29..59	CDD:293786
		ANK repeat	61..92	CDD:293786
		ANK repeat	95..126	CDD:293786
		RCC1	154..201	CDD:278826	16/50 (32%)
		RCC1	205..259	CDD:278826	5/53 (9%)
		RCC1	264..311	CDD:278826	16/47 (34%)
		RCC1	315..365	CDD:278826	16/51 (31%)
		SPOP_C_like	586..>615	CDD:269810	4/32 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910