DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ca and Rcc1

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	XP_006239135.1	Gene:	Rcc1 / 682908	RGDID:	1592835	Length:	434	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	82/339 - (24%)
Similarity:	128/339 - (37%)	Gaps:	91/339 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1111 AIESSRFKP-----------ISAGCAYCACVV-DGTAYFWGS----SGIPSYYSAQKSTEPPEPA 1159
            ::|.|...|           :|||.::.|.:. ||..:.|||    :|:.......|.:..|
  Rat   117 SVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMKKSMVP--- 178

  Fly  1160 HAVKSLDLLSQLNLQVHAIKCGRQHTLILTNNG-LYSLGNNNLCQLG------IGRHMQMALQPM 1217
                   :..||:.||..:..|..|.::||.:| ||:||.....|||      ..|..:..|:.:
  Rat   179 -------VQVQLDTQVVKVASGNDHLVMLTTDGDLYTLGCGEQGQLGRVPELFANRGGRQGLERL 236

  Fly  1218 LVTALDGMNITMLEA--------------GQYHNAAVA-DGKLYMWGWGIYGQL---GQGSCENI 1264
            ||.     ...:|::              |.|...|:: :|.:|.:|...|.||   |.|||
  Rat   237 LVP-----RCVLLKSRGTRGRVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTGSC--- 293

  Fly  1265 ATPQLVSFFK--FKKILQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHG 1327
            ..||.::.||  .|..:..|.|..||:.:    :|..:|       :..|...:|:||.|.....
  Rat   294 FIPQNLTSFKNSTKSWVGFSGGQHHTVCM----DSEGKA-------YSLGRAEYGRLGLGEGAEE 347

  Fly  1328 DTKTNLPVRLEVGD---CSLRLIHTKFFTNLAVDEQDRLFTWGSSPQALRLANQIKRRANAKQKM 1389
            .:...|..||.|..   |...:       ..||.:..|:|.||..         ...:....|:.
  Rat   348 KSIPTLISRLPVVSSVACGASV-------GYAVSKDGRVFAWGMG---------TNYQLGTGQED 396

  Fly  1390 EENQQRELLSKQLE 1403
            :.....|:..||||
  Rat   397 DAWSPVEMTGKQLE 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	67/276 (24%)
		RCC1_2	1175..1200	CDD:290274	10/25 (40%)
		RCC1	1193..1240	CDD:278826	14/66 (21%)
		RCC1	1242..1291	CDD:278826	19/53 (36%)
		RCC1_2	1503..1532	CDD:290274
		RCC1	1522..1568	CDD:278826
		RCC1_2	1558..1584	CDD:290274
Rcc1	XP_006239135.1	ATS1	19..432	CDD:227511	82/339 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910