Protein Alignment ca and herc5.1

DIOPT Version :9

• Sequence 1: NP_001287593.1
• Gene: ca / 43518
• FlyBaseID: FBgn0000247
• Length: 1961
• Species: Drosophila melanogaster
• Sequence 2: XP_017211386.1
• Gene: herc5.1 / 559981
• ZFINID: ZDB-GENE-090311-56
• Length: 884
• Species: Danio rerio
• Alignment Length: 699
• Identity: 145/699 - (20%)
• Similarity: 234/699 - (33%)
• Gaps: 277/699 - (39%)

  Fly  1172 NLQVHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQY 1235
            |.||..|.||.||::.|||:| |:..|.|.|.|||:.:.......|..:.:|.|:.:..:.||..
Zfish     9 NRQVIQIACGDQHSMALTNDGQLFVWGENALGQLGLRKEQAGTQSPRHLQSLCGIPVAQISAGGN 73

  Fly  1236 HNAAVA-DGKLYMWGWGIYGQLGQGSCENIATPQLVSFFKFKKILQISLGHAHTLVLCGAPNSHM 1299
            |:..:: .|.::.||....||||.|...:...|.:|:..|.|||:.||.|..||..|..
Zfish    74 HSFVLSLSGVVFGWGGNSAGQLGLGDTTDRFVPTVVNSLKRKKIVSISCGGEHTAALAK------ 132

  Fly  1300 EANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGDCSLRLIHTKFFTNLAVDEQDRLF 1364
                 |..:|.|||..|||||                           |..|
Zfish   133 -----GGTVFTFGSGGFGQLG---------------------------HNSF------------- 152

  Fly  1365 TWGSSPQALRLANQIKRRANAKQKMEENQQRELLSKQLEATLLPAPIPSTSTLVEPTTSYAAVVA 1429
                                                                             
Zfish   153 ----------------------------------------------------------------- 152

  Fly  1430 GSTPKSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLTPHLV 1494
                       ||                                            || .|.||
Zfish   153 -----------KD--------------------------------------------EH-HPRLV 161

  Fly  1495 DTSEVAG-RILQISSGLFHFCLISSSCTL-YTWGKNLEHQLGTEDKDRRAVLKPSPIDSIERPMY 1557
              :|:.| ::.|::.|..|..:.::|..| |::|..::.|||..::.:::|  |.|:|   :|
Zfish   162 --AELWGSKVSQVTCGRNHTLVSTASPKLIYSFGCGMQGQLGNGEQVKQSV--PLPVD---QP-- 217

  Fly  1558 VDCGSDFT---LVMTTDHVVRAFGGNSNGQCGRDLGPSVERMRQRVVCLPATKRLVRFESQCVEV 1619
            .:...::|   ||...:|....:    ..:.|.:..|.            .|:.::.|::..:|
Zfish   218 TEYNDEYTIQKLVAGENHSFALY----FKELGNEANPD------------PTRGIMTFDNGMIE- 265

  Fly  1620 PVEINLPRPRIRLDQDPVRYLKVMPPYQPHFLQPANI--SF-----DQHCSVGTPNYKSSTEHAA 1677
                     :....:||.:.:|.:   :..|...|::  ||     |.|       |::|.|:.
Zfish   266 ---------QCECGKDPRKAIKDL---KKVFSSAASLNGSFLKTRHDGH-------YQTSEEYC- 310

  Fly  1678 TGQDSDDMLSSLENLSQNDASFSYNAPVLGDA-HSSLDMDYTPEE--QSYVPLPE---------- 1729
             |.|...:.||:..||:|:...|....||.:: ..:|:.:.|.||  :.|:.|||
Zfish   311 -GLDFGLVESSIATLSRNERLISTVLKVLQESLLPTLNPNPTGEESLRLYILLPELISHLKSEQK 374

  Fly  1730 ----QAVGSGM----PANAEQLLGRDDDDGSTYTQSTEGMGESSLQHLRHYIHYCLYAFHGLYNP 1786
                :|:.|.:    ||....|        ..|...   :.:..|::|..........|.|....
Zfish   375 AELTEALASKILNLSPAALRVL--------EIYWSK---LPDDWLKNLVKLFKKASAKFFGRIIV 428

  Fly  1787 DKIGECARPHRNEYRIRICMLNFRFVEAFRLCLQSCGSAQRTLKLFEYF 1835
            :.:...|:.|         ||  :|||..:...|.|.||.|.:|. .||
Zfish   429 ENVNNVAKTH---------ML--KFVEILQRVYQVCCSANRNIKK-RYF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	86/422 (20%)
		RCC1_2	1175..1200	CDD:290274	12/25 (48%)
		RCC1	1193..1240	CDD:278826	13/46 (28%)
		RCC1	1242..1291	CDD:278826	19/48 (40%)
		RCC1_2	1503..1532	CDD:290274	7/29 (24%)
		RCC1	1522..1568	CDD:278826	13/49 (27%)
		RCC1_2	1558..1584	CDD:290274	4/28 (14%)
herc5.1	XP_017211386.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010