DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ca and rcbtb1

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001017352.2	Gene:	rcbtb1 / 550106	XenbaseID:	XB-GENE-987316	Length:	599	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	81/286 - (28%)
Similarity:	126/286 - (44%)	Gaps:	58/286 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1107 DNQFAIESSRFKPI----------SAGCAYCACVVDGTAYFWGSSGIPSYYS------AQKSTEP 1155
            |||..|...|...:          .:|.....|..||..|.||.:|    ||      |.:...|
Frog   127 DNQSTIIPRRLDVLCGKRIVDLSYGSGPHILVCNEDGEVYSWGHNG----YSQLGNGNAIQGVAP 187

  Fly  1156 PEPAHAVKSLDLLSQLNLQVHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLV 1219
            .:..     ::||::..:||   .||..|::.||::| ::..|.||..|:|.|.....::...:.
Frog   188 VQVC-----MELLAKKVIQV---ACGSHHSMALTSDGEVFCWGYNNCGQVGSGTTANQSVPRRVS 244

  Fly  1220 TALDGMNITMLEAGQYHNAAVAD-GKLYMWGWGIYGQLGQGSCENIATPQLVSFFKFKKILQISL 1283
            ..|....:..:.|||..:.||.| |.:|.||:...||||.|:..|...|..:.|.....|:|:.|
Frog   245 ATLQSKVVVSIAAGQSSSMAVTDNGHVYCWGYNGTGQLGIGNTGNQLMPCRLVFAHPVCIIQVVL 309

  Fly  1284 GHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGDCSLRLI- 1347
            |:||||.|...           ..|:.:|:|..||||.||      |:|....::|| .:.|::
Frog   310 GYAHTLALSDQ-----------GVLYAWGANSHGQLGIGN------KSNQTAPVKVG-TNERMVE 356

  Fly  1348 ----HTKFFTNL--AVDEQDRLFTWG 1367
                |:   ||:  |..:..:::.||
Frog   357 VTACHS---TNISAAKSQSGQVYMWG 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	64/219 (29%)
		RCC1_2	1175..1200	CDD:290274	8/25 (32%)
		RCC1	1193..1240	CDD:278826	10/46 (22%)
		RCC1	1242..1291	CDD:278826	21/49 (43%)
		RCC1_2	1503..1532	CDD:290274
		RCC1	1522..1568	CDD:278826
		RCC1_2	1558..1584	CDD:290274
rcbtb1	NP_001017352.2	RCC1	111..153	CDD:278826	5/25 (20%)
		RCC1	162..212	CDD:278826	17/61 (28%)
		RCC1	215..265	CDD:278826	11/49 (22%)
		RCC1	268..317	CDD:278826	20/48 (42%)
		RCC1_2	304..333	CDD:290274	12/39 (31%)
		RCC1	321..362	CDD:278826	14/47 (30%)
		BTB	428..532	CDD:279045
		BTB	439..535	CDD:197585
		SPOP_C_like	535..591	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010