DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ca and CG6678

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	59/228 - (25%)
Similarity:	88/228 - (38%)	Gaps:	75/228 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1145 SYYSAQKSTEPPEPAH---------AVKS----------LDLLSQLNLQVHAIKCGRQHTLILTN 1190
            |.:.|.|:...|...|         |:.|          |...|:...:|..::||.:|.::|..
  Fly   127 SIFGAAKAPSSPIIEHIACGSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLNA 191

  Fly  1191 NG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYHNAAV-ADGKLYMWGWGIY 1253
            || :::.||....|||:. .:::...|.|:.||.|:.||.:.||.:|:||: |.|.||.||....
  Fly   192 NGDVFTWGNGLRGQLGLA-ELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCS 255

  Fly  1254 GQLG-------------------------------QGSCENIATPQLVSFFKFKKILQISLGHAH 1287
            ||||                               .|...:...|           |::..|..|
  Fly   256 GQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAP-----------LRVFAGSRH 309

  Fly  1288 TLVLCGAPNSHMEANHCGNELFVFGSNHFGQLG 1320
            ||::          ..|| .|:|.|....||||
  Fly   310 TLLI----------RRCG-RLWVSGWCKHGQLG 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	55/215 (26%)
		RCC1_2	1175..1200	CDD:290274	9/25 (36%)
		RCC1	1193..1240	CDD:278826	16/46 (35%)
		RCC1	1242..1291	CDD:278826	16/79 (20%)
		RCC1_2	1503..1532	CDD:290274
		RCC1	1522..1568	CDD:278826
		RCC1_2	1558..1584	CDD:290274
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	59/228 (26%)
		RCC1_2	176..205	CDD:290274	9/28 (32%)
		RCC1	192..241	CDD:278826	18/49 (37%)
		RCC1_2	228..257	CDD:290274	13/28 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840