DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ca and Rcbtb1

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001101850.1	Gene:	Rcbtb1 / 361050	RGDID:	1308467	Length:	531	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	80/289 - (27%)
Similarity:	121/289 - (41%)	Gaps:	45/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1101 FRINYE------DNQF--------AIESSRFKPISAGCA--YCACVVDGTAYFWGSSGIPSYYSA 1149
            |.:||.      |||.        |:...|.|.:|.|..  ......||..|.||.:|. |....
  Rat    46 FGLNYSNCLGTGDNQSTLVPKKLEALCGKRIKSLSYGSGPHVLLSTEDGVVYAWGHNGY-SQLGN 109

  Fly  1150 QKSTEPPEPAHAVKSLDLLSQLNLQVHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMA 1213
            ..:.:...|.....:|     |..||..:.||..|::.|..:| |::.|.||..|:|.|......
  Rat   110 GTTNQGIAPIQVCTNL-----LVKQVVEVACGSHHSMALAADGELFAWGYNNCGQVGSGSTANQP 169

  Fly  1214 LQPMLVTALDGMNITMLEAGQYHNAAVAD-GKLYMWGWGIYGQLGQGSCENIATPQLVSFFKFKK 1277
            ....:...|....:..:..||..:.||.| |::|.||:...||||.|:..|..||..|:......
  Rat   170 TPRKVTNCLHTKKVVNIACGQTSSMAVLDSGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHGVC 234

  Fly  1278 ILQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVR----LE 1338
            :.||..|:||||.|...           ..|:.:|:|.:||||||:.::..:.|.:.|.    :|
  Rat   235 VNQIVCGYAHTLALTDE-----------GLLYAWGANTYGQLGTGSKNNLLSPTQIMVEKERVIE 288

  Fly  1339 VGDCSLRLIHTKFFTNLAVDEQDRLFTWG 1367
            :..|     |:. .|:.|..:...::.||
  Rat   289 IAAC-----HST-HTSAAKTQGGHVYMWG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	62/216 (29%)
		RCC1_2	1175..1200	CDD:290274	8/25 (32%)
		RCC1	1193..1240	CDD:278826	10/46 (22%)
		RCC1	1242..1291	CDD:278826	21/49 (43%)
		RCC1_2	1503..1532	CDD:290274
		RCC1	1522..1568	CDD:278826
		RCC1_2	1558..1584	CDD:290274
Rcbtb1	NP_001101850.1	RCC1	42..89	CDD:395335	11/42 (26%)
		ATS1	<91..363	CDD:227511	69/244 (28%)
		BTB_POZ_RCBTB1_CLLD7	350..466	CDD:349662
		BACK_RCBTB1	466..531	CDD:350603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.800