Protein Alignment ca and Rcc1l

DIOPT Version :9

• Sequence 1: NP_001287593.1
• Gene: ca / 43518
• FlyBaseID: FBgn0000247
• Length: 1961
• Species: Drosophila melanogaster
• Sequence 2: NP_001101802.1
• Gene: Rcc1l / 360796
• RGDID: 1307558
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 111/543 - (20%)
• Similarity: 167/543 - (30%)
• Gaps: 234/543 - (43%)

  Fly  1110 FAIESS------------RFKPI-----------SAGCAYCACVVDG----TAYFWG-----SSG 1142
            |.:.||            |.:|:           ||.|.|...::..    ....||     .|.
  Rat    74 FVVPSSGPGPRAGLRPRRRIQPVPYRLELDHKISSAACGYGFTLLSSKTKDVTKVWGMGLNKDSQ 138

  Fly  1143 IPSYYSAQKST-------EP-PEPAHAVKSLDLLSQLNLQVHAIKCGRQHTLILTN-NGLYSLGN 1198
            :..:.|.:..|       || |.|      |.|......:|..:.|||.|:|:||: .|::|:||
  Rat   139 LGFHRSRKDKTRGYEYVLEPSPVP------LPLDRPQETKVLQVSCGRAHSLVLTDREGVFSMGN 197

  Fly  1199 NNLCQLG---------IGRHMQMALQPMLVTALDGMNITMLEAGQYHNAAVAD-GKLYMWGWGIY 1253
            |...|.|         ...|....:|.     .:| .:..:..||.|:..:.| |::|..|||..
  Rat   198 NAHGQCGRKVVEDEVYSESHKVHRMQD-----FEG-QVVQVVCGQDHSLFLTDKGEVYSCGWGAD 256

  Fly  1254 GQLGQGSCENIATP-QLVSFFKFKKILQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFG 1317
            ||.|.|.....:|| :|........::|::......|.|                     |...|
  Rat   257 GQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLAL---------------------SADGG 300

  Fly  1318 QLGTGNSDH-------GDTKTNLPVRLE---VG----------DCSLRLIHTKFFTNLAVDEQDR 1362
            ..|.|||::       ..|:.|:|..|.   ||          .|::            ::|:..
  Rat   301 VFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGKVKQVACGGTGCAI------------LNEEGH 353

  Fly  1363 LFTWGSSPQALRLANQIKRRANAKQKMEENQQRELLSK--QLEATLLPAPIPSTSTLVEPTTSYA 1425
            :|.||..                           :|.|  .|..|.||..||.|
  Rat   354 VFVWGYG---------------------------ILGKGPNLSETALPEMIPPT----------- 380

  Fly  1426 AVVAGSTPKSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLT 1490
              :.|.|                                                 |.:|
  Rat   381 --LFGLT-------------------------------------------------EFNP----- 389

  Fly  1491 PHLVDTSEVAGRILQISSGLFHFCLISSSCTLYTWGKNLEHQLG---TEDK--DRRAVLKPSPID 1550
                   ||  ::.||..||.||..:::...|:.||||:...||   .||:  ..|..:...|:|
  Rat   390 -------EV--KVSQIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVD 445

  Fly  1551 SIERPMYVDCGSDFTLVMTTDHV 1573
                   |.||.|..:.:....:
  Rat   446 -------VACGVDHMVTLAKSFI 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	94/455 (21%)
		RCC1_2	1175..1200	CDD:290274	12/25 (48%)
		RCC1	1193..1240	CDD:278826	12/55 (22%)
		RCC1	1242..1291	CDD:278826	15/50 (30%)
		RCC1_2	1503..1532	CDD:290274	11/28 (39%)
		RCC1	1522..1568	CDD:278826	16/50 (32%)
		RCC1_2	1558..1584	CDD:290274	4/16 (25%)
Rcc1l	NP_001101802.1	RCC1	127..186	CDD:278826	17/64 (27%)
		RCC1_2	173..202	CDD:290274	13/28 (46%)
		RCC1	192..242	CDD:278826	12/55 (22%)
		RCC1_2	229..258	CDD:290274	9/28 (32%)
		RCC1	245..295	CDD:278826	14/49 (29%)
		RCC1	298..348	CDD:278826	12/61 (20%)
		RCC1_2	393..422	CDD:290274	11/28 (39%)
		RCC1	409..452	CDD:278826	15/49 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910