DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ca and K11D2.1

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001368497.1	Gene:	K11D2.1 / 187290	WormBaseID:	WBGene00010768	Length:	278	Species:	Caenorhabditis elegans

Alignment Length:	148	Identity:	37/148 - (25%)
Similarity:	65/148 - (43%)	Gaps:	19/148 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1175 VHAIKCGRQHTLIL---TNNGLYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYH 1236
            |..::....|..::   |...|:|:|.....:||:|. ::...:|:.:..|.|:.|..:..|.:|
Worm   131 VRIVEAAAGHDFLIFRDTTGNLFSMGTGTRGELGVGL-IRRVDEPVHIEQLVGIRIKKVACGGWH 194

  Fly  1237 NAAVAD-GKLYMWGWGIYGQLGQGSCENIATPQLV----SFFKFKKILQISLGHAHTLVLCGAPN 1296
            ..|:.: |..|.|||..|||||:........|.|:    ..|..:.||.::....:|.::.
Worm   195 TVALTEGGDAYTWGWNRYGQLGKDKGSTEVYPVLIDPEEEKFGEENILDVACTEHNTQIVI---- 255

  Fly  1297 SHMEANHCGNELFVFGSN 1314
                  ..|:..||.|:|
Worm   256 ------KTGHAPFVLGTN 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	37/148 (25%)
		RCC1_2	1175..1200	CDD:290274	6/27 (22%)
		RCC1	1193..1240	CDD:278826	12/46 (26%)
		RCC1	1242..1291	CDD:278826	16/53 (30%)
		RCC1_2	1503..1532	CDD:290274
		RCC1	1522..1568	CDD:278826
		RCC1_2	1558..1584	CDD:290274
K11D2.1	NP_001368497.1	ATS1	<118..>259	CDD:227511	32/138 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910