Protein Alignment ca and ran-3

DIOPT Version :9

• Sequence 1: NP_001287593.1
• Gene: ca / 43518
• FlyBaseID: FBgn0000247
• Length: 1961
• Species: Drosophila melanogaster
• Sequence 2: NP_495753.1
• Gene: ran-3 / 174332
• WormBaseID: WBGene00004304
• Length: 569
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 109/508 - (21%)
• Similarity: 170/508 - (33%)
• Gaps: 143/508 - (28%)

  Fly  1117 FKPISAGCAYCACVVDGTAYFWGSSGIPSYYSAQKSTEPPEPAHAVKSLDLLSQLNLQVHAIKCG 1181
            |.|...|....:|   |.....|..|       :.:|:.|      :.:|:..:..|:......|
 Worm   145 FAPSIIGDRVLSC---GEGEALGHPG-------RTTTKKP------RKVDIFEEEGLKPLQAVAG 193

  Fly  1182 RQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGM-----------------NIT 1228
            ..|:.:||:.| :|..|.|           :....|......:|.                 .|.
 Worm   194 GVHSAVLTSEGEVYMCGIN-----------EKGTVPAEGVEKEGSTDEFAKVKFEEDIEKEGKIV 247

  Fly  1229 MLEAGQYHNAAVAD-GKLYMWGWGIYGQLGQGSCENI-----ATPQLVSFFKFKKILQISLGHAH 1287
            ||.||....||:.| |.:..|| .:....|......:     ..|.::.....:||::|:.|..|
 Worm   248 MLAAGASFTAALTDQGSVIAWG-NLRNSNGNVDVHPLLHKMQEAPVVIVHQAKRKIVKIAAGENH 311

  Fly  1288 TLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRL-----EVGD---CSL 1344
            .::|        :...|   |..||....||||..:.    |||   :|.     |.||   ..|
 Worm   312 LVML--------DEKGC---LLTFGDGEMGQLGRSSR----TKT---IRSKYMCDESGDHLLVPL 358

  Fly  1345 RLIHT-KFFTNLAVD------------EQDRLFTWGSSPQALRLANQIKRRANAKQKMEENQQRE 1396
            |..|. |||..:|.:            |..:.:.:|.:..| :|..::. .|:..|..::|  ||
 Worm   359 RFKHKGKFFDVVAKNVFASGFWTIVHGEDGKYYAFGLNNYA-QLGIKVD-EADVGQDGQDN--RE 419

  Fly  1397 LLSKQLEATLLPAPIP---STSTLVEPTTSYAAVVAGSTPK--SSVSDTKDCQDVQNEAAPSDAT 1456
            |      ...|||..|   :..|.|........|:.||..|  :...:|.:...:.|.....|
 Worm   420 L------RVFLPAEAPAFGAERTFVNIEGVQHVVILGSDGKVFAMGKNTDNALGLGNWTGKDD-- 476

  Fly  1457 ETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLTPHLVDTSEVAGRILQISSGLFHFCLISSSCT 1521
                                         .:|.....:...|...:|:.:|:.|......|...|
 Worm   477 -----------------------------QQHWLYDTIQEIEFDSKIVGVSAKLATSIAWSEDGT 512

  Fly  1522 LYTWGKNLEHQ--LGTEDKDRRAVLKPSPIDSIERPMYVDCGSDF----TLVM 1568
            .|.||.:...|  ||.:|:|.:.|.||..|.|.....|...|:..    ||::
 Worm   513 AYAWGFDTTGQLGLGLKDEDEKMVSKPEEISSAHLDGYSIIGASISDQHTLII 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	100/467 (21%)
		RCC1_2	1175..1200	CDD:290274	7/25 (28%)
		RCC1	1193..1240	CDD:278826	11/63 (17%)
		RCC1	1242..1291	CDD:278826	11/54 (20%)
		RCC1_2	1503..1532	CDD:290274	8/28 (29%)
		RCC1	1522..1568	CDD:278826	17/51 (33%)
		RCC1_2	1558..1584	CDD:290274	3/15 (20%)
ran-3	NP_495753.1	ATS1	163..569	CDD:227511	104/487 (21%)
		RCC1_2	189..215	CDD:290274	8/36 (22%)
		RCC1_2	246..276	CDD:290274	11/30 (37%)
		RCC1_2	302..331	CDD:290274	9/39 (23%)
		RCC1	510..565	CDD:278826	18/54 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910