Protein Alignment ca and herc-1

DIOPT Version :9

• Sequence 1: NP_001287593.1
• Gene: ca / 43518
• FlyBaseID: FBgn0000247
• Length: 1961
• Species: Drosophila melanogaster
• Sequence 2: NP_490834.1
• Gene: herc-1 / 171700
• WormBaseID: WBGene00021685
• Length: 1019
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 121/644 - (18%)
• Similarity: 201/644 - (31%)
• Gaps: 279/644 - (43%)

  Fly  1175 VHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYHNA 1238
            |.::.||.|||:.||.:| ::|:|:|...|||.|...:.:.....|:......|..:.||:.|..
 Worm    43 VTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYPVSWTSSAKIIQISAGRSHTV 107

  Fly  1239 AVA-DGKLYMWGWGIYGQLG-------QGSCENIATPQLVSFFKFKKILQISLGHAHTLVLCGAP 1295
            :|. ||:::.||...:||||       ||      ||:.|.  :...|:|::.|
 Worm   108 SVTDDGRVFAWGSNEHGQLGMESKFTWQG------TPRRVQ--EINDIVQVASG----------- 153

  Fly  1296 NSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGDCSLRLIHTKFFTNLAVDEQ 1360
                 :|||                                                  :|:||.
 Worm   154 -----SNHC--------------------------------------------------IALDEG 163

  Fly  1361 DRLFTWGSSPQALRLANQIKRRANAKQKMEENQQRELLSKQLEATLLPAPIPSTSTLVEPTTSYA 1425
            .|:|.||                      |:...|
 Worm   164 GRVFVWG----------------------EQADGR------------------------------ 176

  Fly  1426 AVVAGSTPKSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVASPPVLVPEPDPTEHLT 1490
                             |                                    :..|:|.|.|:
 Worm   177 -----------------C------------------------------------IHRPEPVEQLS 188

  Fly  1491 --PHLVDTSEVAGRILQISSGLFHFCLISSSCTLYTWGKNLEHQLGTEDKDRRAVLKPSPIDSIE 1553
              |           |:::.:|..|...:|:|..::|||:|...:||.:|      |:|.  .|::
 Worm   189 GVP-----------IVRVLAGARHCLALSASGAVFTWGQNNSGELGIDD------LRPQ--TSVQ 234

  Fly  1554 RPMYVD--------CGSDFTLVMTTDHVVR--AFGGNSNGQCGRDLGPSVE-RMRQRVVCLPATK 1607
            ....:|        ||.:.|:::|  |..|  :||.::.||||  .|..|| |.....|......
 Worm   235 HVHQMDGLGVVEAACGDNHTVLLT--HCGRTFSFGSDALGQCG--FGKKVEKRTNPTAVSDLIGS 295

  Fly  1608 RLVRFESQ-------CVEVPVEINL----------------PRPRIRLDQDPVRYLKVMPPYQPH 1649
            .:.|..:.       |...|....|                ||....||    ....|...|...
 Worm   296 HVTRIAAGACHTIAICKGAPYPFGLNSSGQLGNGKIMTQSTPRKTDELD----HVTGVFAGYHQT 356

  Fly  1650 FLQPANISFDQHCSVGTP---NYKSSTEHAATGQ-----DSDDMLSSLENLSQNDASFS------ 1700
            |...::.:.:|:..||..   .|....:|.:..:     |:.:::|.:|::..:.||.:
 Worm   357 FFVRSSGTIEQNEIVGPSCPMQYPIKLDHESLKKLLDEGDALEVMSLIESVFSSLASMNMSFLYK 421

  Fly  1701 ----YNAPVLGDAHSSLDMDYT----------PEEQSYVPLPEQAVGSGMPANAEQLLG 1745
                ||.....:....:|||..          |.::.|:.|...::.......:|.|.|
 Worm   422 DERRYNVGFCFERSHGIDMDQVMEAFMLFDEYPMKRQYMELIVDSLKIAFQEWSENLKG 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ca	NP_001287593.1	ATS1	1158..1588	CDD:227511	84/433 (19%)
		RCC1_2	1175..1200	CDD:290274	11/25 (44%)
		RCC1	1193..1240	CDD:278826	12/46 (26%)
		RCC1	1242..1291	CDD:278826	16/55 (29%)
		RCC1_2	1503..1532	CDD:290274	9/28 (32%)
		RCC1	1522..1568	CDD:278826	14/53 (26%)
		RCC1_2	1558..1584	CDD:290274	9/35 (26%)
herc-1	NP_490834.1	ATS1	2..359	CDD:227511	100/521 (19%)
		HECTc	667..1016	CDD:238033

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010