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Protein Alignment ca and Ibtk

DIOPT Version :9

Sequence 1:	NP_001287593.1	Gene:	ca / 43518	FlyBaseID:	FBgn0000247	Length:	1961	Species:	Drosophila melanogaster
Sequence 2:	NP_001074751.1	Gene:	Ibtk / 108837	MGIID:	1918677	Length:	1352	Species:	Mus musculus

Alignment Length:	700	Identity:	145/700 - (20%)
Similarity:	233/700 - (33%)	Gaps:	207/700 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1136 YFWG-SSGIPSYYSAQKSTEPPEPAHAVKSLDLLSQLNLQVHAIKCGRQHTLILTNNG-LYSLGN 1198
            |.|| ::.....:.:|.|...||      .|||.|:..:.|..:...:.|::.|:..| :|:.|:
Mouse   145 YTWGDNTNFTLGHGSQNSKHHPE------LLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGH 203

  Fly  1199 NNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYHNAAVA-DGKLYMWGWGIYGQLG----Q 1258
            ....:||.|.. |..|.|.||..|.|.|.:.:.|.:.|...:. ||.:|.:|..::.|||    .
Mouse   204 GRGGRLGHGDE-QTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPP 267

  Fly  1259 GSCENIATPQLVSFFKFKKILQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLG--- 1320
            .|| |:.......:.|.:.|:.::.|..||::..      .||      ::..|.|. ||||
Mouse   268 ASC-NVPRQIQAKYLKGRTIIGVAAGRFHTVLWT------REA------VYTLGLNG-GQLGHLL 318

  Fly  1321 --------------------------TGNSD--------HGD-------------TK-TNLPVRL 1337
                                      ...||        .||             || .||...|
Mouse   319 DPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVL 383

  Fly  1338 EVGDCSLRLIHTKFFTN--------LAVDEQDRLFTWGSSPQALRLA-----------------N 1377
            ..|.|....:..:..|.        ||:|...|:|.|.|...:|:..                 |
Mouse   384 VSGGCMEYKVDPEHLTENGGQKICVLAMDGAGRVFCWRSISSSLKQCRWAYPRQVSISDIALNRN 448

  Fly  1378 QI----KRRANAKQKMEENQQRELLSKQLEATLLP---------APIPSTSTLVEPTTSYAAVVA 1429
            :|    :.....|.|..|::::   :.:.:|.:||         :.:|.|:::      |..:..
Mouse   449 EILFVTQDGEGFKGKWFEDKRK---NSEKKADILPNLHHSSSDVSCVPDTNSV------YERIRL 504

  Fly  1430 GSTP--KSSVSDTKDCQDVQNEAAPSDATETIAPASAKAAPPPVPVASPP-------VLVPEPDP 1485
            ...|  ..:||.:.|         ||.....|..:..|.:...:||.|..       .|:.|.|.
Mouse   505 EKLPFAHRAVSVSTD---------PSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDE 560

  Fly  1486 TEHLTPHLVDTSEVAGR-------ILQISSGLFHFCLISSSCTLYTWGKNLE-HQLGTEDKDRRA 1542
            .:..  |.| |.:|..|       ||.:.|..|....:|.       |.:|| ..:..:|:|...
Mouse   561 MDSF--HDV-TFQVGNRHFPAHKYILAVRSDFFQKLFLSD-------GSSLELTDVYQKDEDAAG 615

  Fly  1543 V-------LKPSPIDSIERPMYVDCGSDFTLVMTTDHVVRAFGGNSNGQCGRDLGPSVERMRQRV 1600
            .       :.|...:.:.:.||.|.....|.......:|:....:..|        |.:.....|
Mouse   616 CHLFVVEKVHPDLFEYLLQFMYTDTCDLLTHGFKPRMIVKRKAEDCEG--------SPDSHLHTV 672

  Fly  1601 VCLPATKRLVRFE---SQCVEVPVEINLPRPRIRL------DQDPVRYLKVMPPYQPHFLQPANI 1656
            .|....|:...||   |.......|....:|:...      |.||||.|:.:..
Mouse   673 NCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGDDDPVRMLQSVAK----------- 726

  Fly  1657 SFDQHCSVGTPNYKSSTEHAATGQDSDDMLSSLE----NLSQNDASFSYN 1702
                  ..|..|..|..|......:..::::...    .|||...||.|:
Mouse   727 ------KFGLSNLSSRLEGVRLENEKINVIAKKTGNKLKLSQKKCSFLYD 770

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.