DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and KAC1

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001078565.1	Gene:	KAC1 / 830911	AraportID:	AT5G10470	Length:	1274	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	142/528 - (26%)
Similarity:	222/528 - (42%)	Gaps:	117/528 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 AGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKV-----------------LK 210
            :|....|..:....|.|:|.....|              ||.::.:                 ||
plant    16 SGFEPRKSSSNASFAESTGHRTTGP--------------LLRRNSISTPSLPPKQAIASKVNGLK 66

  Fly   211 TKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSDNECLQRQVKQHTAKIETITSTLGRT 275
            .|.:...||..||......|:|..|                           ||::.:|..||..
plant    67 EKVKLAKEDYLELRQEATDLQEYSN---------------------------AKLDRVTRYLGVL 104

  Fly   276 KEELSELQAIHEKVKTEHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHN 340
            .|:..:|         :...|.||.     |...|:.                     |:|.|.|
plant   105 AEKSRKL---------DQFVLETEA-----RISPLIN---------------------EKKRLFN 134

  Fly   341 TVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPL 405
            .::..:|||:||||.||..|.|...:.   .:..:.|:.:.:.|....:.  ::.|.||:|:.|.
plant   135 DLLTAKGNIKVFCRARPLFEDEGPSVI---EFPGDCTICVNTSDDTLSNP--KKDFEFDRVYGPH 194

  Fly   406 SSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRN 470
            ..|:.:|..|.|.:||||||.|:.|.:||||.:||||||:|.....|:..|..:.|||.......
plant   195 VGQAALFSDVQPFVQSALDGSNVSILSYGQTNAGKTYTMEGSNHDRGLYARCFEELFDLANSDST 259

  Fly   471 LGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIY--VSNITEETVLDPNHLRHLMH 533
            ....:....:..|||||.:.||||..|.::     .|...|::  |..:.:|.|.:|.....::.
plant   260 STSRFSFSLSVFEIYNEQIRDLLSETQSNL-----PNINMDLHESVIELGQEKVDNPLEFLGVLK 319

  Fly   534 TAKMNRATASTAGNERS--SRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSE----SPKTSTR 592
            :|.:||      ||.:|  :.:|.:..:.:...:....|.....::||||||||    ...:...
plant   320 SAFLNR------GNYKSKFNVTHLIVSIHIYYSNTITGENIYSKLSLVDLAGSEGLIMENDSGDH 378

  Fly   593 MTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQES 657
            :|:..::..|:|.|.:|:.:|...:|.|||.||.||.:|..||||:|||||.:|:.|......|:
plant   379 VTDLLHVMNSISALGDVLSSLTSGKDSIPYDNSILTRVLADSLGGSSKTLMIVNICPSVQTLSET 443

  Fly   658 VKSLRFAA 665
            :..|.:||
plant   444 ISCLNYAA 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	108/328 (33%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	107/326 (33%)
KAC1	NP_001078565.1	Motor_domain	140..457	CDD:277568	108/328 (33%)
KAC1	NP_001078565.1	Kinesin	148..456	CDD:278646	102/320 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D364605at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820