DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and kif15

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_002666969.1	Gene:	kif15 / 573988	ZFINID:	ZDB-GENE-050622-16	Length:	1376	Species:	Danio rerio

Alignment Length:	391	Identity:	137/391 - (35%)
Similarity:	200/391 - (51%)	Gaps:	61/391 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 MDLRGN-------------IRVFCRIRP-----PLESEENRMCCTWTYHDESTVELQSIDAQAKS 389
            |:|:|.             |:||.|:||     .|.::.:...|. |.....||.|.       .
Zfish     1 MNLKGKATAEANTNSDGDAIKVFVRVRPLTQGTGLSTDGDHSLCL-TVSSPQTVRLH-------C 57

  Fly   390 KMGQQIFSFDQVFHPLSSQSDIFEMVSP-LIQSALDGYNICIFAYGQTGSGKTYTMDGVPESV-- 451
            |...:.|::|.|....:||.::|..|:. :::|.::|||..||||||||||||:||.| |..:
Zfish    58 KPEPRTFTYDHVADMNTSQEEVFSSVAKNIVESCMNGYNGTIFAYGQTGSGKTFTMLG-PSELDN 121

  Fly   452 ------GVIPRTVDLLFDSI-RGYRNLGW--EYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKN 507
                  |||||:.:.||..| |.....|.  .:..|.:|:|||||.:||||.:....:.:|  ::
Zfish   122 FSDELRGVIPRSFEYLFFLINREVERSGGTKSFLCKCSFIEIYNEQIYDLLDSVSTSLFLR--ED 184

  Fly   508 NKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEIS 572
            .|..::|....|:..........::.....||..|||:.|..|||||||..:.|..:...::.::
Zfish   185 IKRGVFVEGSVEKYAASAAEAYQVLSMGWRNRRVASTSMNRESSRSHAVFTMTLESKETGQEVVN 249

  Fly   573 V--GSINLVDLAGSESPKTS----TRMTETKNINRSLSELTNVILALLQ----KQDHIPYRNSKL 627
            :  ..:|||||||||..:.:    :|:.|..:|||||..|..||:||:.    |..||.||:|||
Zfish   250 IRTSQLNLVDLAGSERQRDTHTEGSRLKEASSINRSLMCLGQVIMALMDVSNGKNRHICYRDSKL 314

  Fly   628 THLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSSTQS 692
            |.||..|||||:||.:..||.|...||.|::.:|:||   ...|:.|       |.::.|..||.
Zfish   315 TFLLRDSLGGNAKTYIIANVHPGSKCFGETLSTLQFA---QRAKLIK-------NKAMVNEDTQG 369

  Fly   693 N 693
            |
Zfish   370 N 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	128/365 (35%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	129/369 (35%)
kif15	XP_002666969.1	KISc_KLP2_like	18..367	CDD:276824	131/369 (36%)
		KISc	19..364	CDD:214526	130/365 (36%)
		SbcC	371..1007	CDD:223496	137/391 (35%)
		Kinesin-relat_1	462..547	CDD:289481
		Ax_dynein_light	<602..658	CDD:287215
		GBP_C	<707..805	CDD:303769
		Mplasa_alph_rch	709..1360	CDD:275316
		coiled coil	776..788	CDD:293879
		coiled coil	794..805	CDD:293879
		HMMR_C	1262..>1372	CDD:292530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840