Protein Alignment ncd and kif25

DIOPT Version :10

• Sequence 1: NP_476651.1
• Gene: ncd / 43517
• FlyBaseID: FBgn0002924
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_686502.2
• Gene: kif25 / 558219
• ZFINID: ZDB-GENE-041001-167
• Length: 592
• Species: Danio rerio
• Alignment Length: 622
• Identity: 168/622 - (27%)
• Similarity: 256/622 - (41%)
• Gaps: 190/622 - (30%)

  Fly   201 DLLEKHKV--LKTKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSDNECL--------- 254
            |.:..|:|  |:.|...:.|.:.||        ||:|.|:....:        |||
Zfish     8 DQIFAHQVHLLEHKLRSKEERILEL--------ETENALLHLRLA--------ECLGKLHHQRDV 56

  Fly   255 ----QRQVKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALS---TEVVHLRQRTEELLR 312
                |||..|...|::                       |:.|||||   :||..|:|...::..
Zfish    57 EIHFQRQKHQQQRKVQ-----------------------KSTHAALSKLLSEVQILKQGLRDVFS 98

  Fly   313 CNEQQAAELETCKEQLF--------------------------------------QSNMERKELH 339
            .....|.|||...:|||                                      :..:.|:.||
Zfish    99 IYVGFAKELEDQSKQLFKYVGTAKKQDLQSDDLQKLQVQVTTLERSLQEEKERCREERVRRRVLH 163

  Fly   340 NTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSID--------AQAKSKMGQQIF 396
            ||:::|||||||.||:||.|..::.....|..........:|:|.        |:..|.:..:||
Zfish   164 NTLVELRGNIRVHCRVRPILHFDQTPGSPTANGSSSCDAVVQAISDDSVIVNCAKPSSPVTNKIF 228

  Fly   397 SFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDG---------VPES-V 451
            .|::|..|..:|..:||.|.||:.|.|||||:||.||||||||||:||.|         |.:| .
Zfish   229 EFERVHGPEDNQEIVFEEVKPLLTSLLDGYNVCIMAYGQTGSGKTHTMIGSQCEEASAAVQDSQQ 293

  Fly   452 GVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSN 516
            |:||:..:.||..|.  ......:.::.:.:|:||..:.|||:.::....:.:    |.::..::
Zfish   294 GIIPKAANELFKLIS--EKPAGSHTVEMSVVEVYNNEVVDLLARDEDGATVGV----KREVITTS 352

  Fly   517 --------ITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIG---------- 563
                    ::.|.|.....:..|:.:....|:.:.|..:..|||||.:..|.:..
Zfish   353 TGTSEVPCLSYELVRSSAEVMQLISSVLKLRSHSPTLVHMDSSRSHFIVTLTVTSKSPDALAVAR 417

  Fly   564 -----------------------RHAEKQEISVGS--------------------------INLV 579
                                   |.|..:..|..|                          :.||
Zfish   418 RLQNARQDVQRVSQKEWWSPRCRRAASSRSSSPASSPCHSPCHSPCPSPRPSITQAPLKTKLQLV 482

  Fly   580 DLAGSE----SPKTSTRMTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLGGNSK 640
            ||||||    |..|...:.|:..||||||.|::|:.||.:::.|:|||||||||||..::||::|
Zfish   483 DLAGSECVGMSGVTGAALWESSCINRSLSALSDVLGALAERRPHVPYRNSKLTHLLQDAIGGDAK 547

  Fly   641 TLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKR 677
            .|:.:.|||.|....||::||.|.......:....:|
Zfish   548 LLIMLCVSPTQRFLTESLQSLGFGTRARQVQREPPRR 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_476651.1	PRK03918	<204..350	CDD:235175	45/201 (22%)
		KISc_C_terminal	346..672	CDD:276817	124/414 (30%)
kif25	XP_686502.2	Motor_domain	170..577	CDD:473979	124/412 (30%)