DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and cmet

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_524993.3	Gene:	cmet / 53561	FlyBaseID:	FBgn0040232	Length:	2189	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	113/355 - (31%)
Similarity:	180/355 - (50%)	Gaps:	40/355 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 NIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIF 412
            :|:|..::||.    |..:...|...:..::.|....|:.        :.||.||...:|..::|
  Fly     8 SIQVCIKVRPC----EPGLTSLWQVKERRSIHLADSHAEP--------YVFDYVFDEGASNQEVF 60

  Fly   413 E-MVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNLGWEYE 476
            : |...::.:.:.|:|..|||||||.|||||||.|..::.||:......:|..|......  ::.
  Fly    61 DRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETER--DFL 123

  Fly   477 IKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRAT 541
            ::..::|||||.:||||:.:.:|::|.   .:.|.|...|..|..:.....|..|:......|..
  Fly   124 LRVGYIEIYNEKIYDLLNKKNQDLKIH---ESGNGIVNVNCEECIITSEVDLLRLLCLGNKERTV 185

  Fly   542 ASTAGNERSSRSHAVTKLELIGR---HAEKQEISVGSINLVDLAGSE----SPKTSTRMTETKNI 599
            ..|..|||||||||:.|:.:..|   |::...:....:|||||||||    :.....|:.|..:|
  Fly   186 GETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHI 250

  Fly   600 NRSLSELTNVILALLQKQDH--IPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLR 662
            |:||..|:|||.:|.:..|:  ..||:||||.:|..|||||:.|.:...:.|  ...:||..:|.
  Fly   251 NKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKP--SIMEESQSTLS 313

  Fly   663 FAASVNSCKMTKAKRNR---YLNNSVANSS 689
            ||        |:||:.|   .:|..|::::
  Fly   314 FA--------TRAKKIRIKPQVNEMVSDAT 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	107/333 (32%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	110/339 (32%)
cmet	NP_524993.3	KISc	8..328	CDD:214526	111/346 (32%)
		Motor_domain	8..321	CDD:277568	110/339 (32%)
		Smc	<680..1449	CDD:224117
		TMPIT	779..>867	CDD:285135
		Smc	1042..1910	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930