DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and Klp64D

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_523934.1	Gene:	Klp64D / 38611	FlyBaseID:	FBgn0004380	Length:	677	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	128/376 - (34%)
Similarity:	200/376 - (53%)	Gaps:	29/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 NIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIF 412
            |:||..|.||..::|.:....:....|:....:..:...|.:....:.:.||.||...|:|.|::
  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDLY 84

  Fly   413 -EMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPES---VGVIPRTVDLLFDSIRGYRNLGW 473
             :...|::...|:|||..|.||||||:||||||.|.|:|   .|:||.....:|..|...:. ..
  Fly    85 VDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKE-NQ 148

  Fly   474 EYEIKATFLEIYNEVLYDLLSNE-QKDMEIRMAKNNKNDI--YVSNITEETVLDPNHLRHLMHTA 535
            ::.::.:::|||||.:.|||..: .|.:|::    .:.||  :|.:::...|.:.:.|.::|...
  Fly   149 KFLVRVSYMEIYNEEVRDLLGKDVGKSLEVK----ERPDIGVFVKDLSGYVVHNADDLENIMRLG 209

  Fly   536 KMNRATASTAGNERSSRSHAVTKLEL----IGRHAEKQEISVGSINLVDLAGSE-SPKTST---R 592
            ..|||..:|..|:.||||||:..:.:    :| ..:.|.:.:|.:.|||||||| ..||..   |
  Fly   210 NKNRAVGATKMNQESSRSHAIFSITVERSELG-EGDVQHVRMGKLQLVDLAGSERQSKTQASGQR 273

  Fly   593 MTETKNINRSLSELTNVILALLQ-KQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQE 656
            :.|...||.|||.|.|||.||:. |..||||||||||.||..||||||||:|...:||....:.|
  Fly   274 LKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYME 338

  Fly   657 SVKSLRFAASV----NSCKMTKAKRN---RYLNNSVANSSTQSNNSGSFDK 700
            ::.:||:|:..    |...:.:..::   |:....:|....|.....|.::
  Fly   339 TISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEE 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	124/343 (36%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	124/349 (36%)
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	123/337 (36%)
		Kinesin	26..352	CDD:278646	120/331 (36%)
		RILP-like	<437..556	CDD:304877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840