DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and Khc

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_476590.1	Gene:	Khc / 36810	FlyBaseID:	FBgn0001308	Length:	975	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	137/362 - (37%)
Similarity:	190/362 - (52%)	Gaps:	34/362 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 NIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIF 412
            :|:|.||.||..:||| :....:.....:.||...|....|      ::.||:||.|.:||..::
  Fly    12 SIKVVCRFRPLNDSEE-KAGSKFVVKFPNNVEENCISIAGK------VYLFDKVFKPNASQEKVY 69

  Fly   413 -EMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGV-PESV--GVIPRTVDLLFDSIRGYR-NLG 472
             |....::...|.|||..|||||||.||||:||:|| .:||  |:|||.|:.:|:.|.... ||
  Fly    70 NEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNL- 133

  Fly   473 WEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKM 537
             |:.||.::.|||.:.:.|||...:.::.:...||...  ||...||..|..|..:..::...|.
  Fly   134 -EFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVP--YVKGATERFVSSPEDVFEVIEEGKS 195

  Fly   538 NRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSES-PKT---STRMTETKN 598
            ||..|.|..||.|||||:|..:.:...:.|.|:...|.:.||||||||. .||   .|.:.|.||
  Fly   196 NRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKN 260

  Fly   599 INRSLSELTNVILALLQ-KQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQES----- 657
            ||:|||.|.|||.||.. .:.|||||:||||.:|..|||||::|.:.|..||..  |.||
  Fly   261 INKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPAS--FNESETKST 323

  Fly   658 ------VKSLRFAASVNSCKMTKAKRNRYLNNSVANS 688
                  .|:::....||.....:..:.||......|:
  Fly   324 LDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNA 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	134/344 (39%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	134/350 (38%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	132/333 (40%)
		KISc	12..340	CDD:214526	132/340 (39%)
		Apolipoprotein	595..744	CDD:279749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437974
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840