Protein Alignment ncd and CG5004

DIOPT Version :10

• Sequence 1: NP_476651.1
• Gene: ncd / 43517
• FlyBaseID: FBgn0002924
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Alignment Length: 828
• Identity: 171/828 - (20%)
• Similarity: 288/828 - (34%)
• Gaps: 223/828 - (26%)

  Fly    15 QMPIKT--VLPTDRIRAGLGGGAAGAGAFNVNANQTYCG----NLLPPLSRDLNNLPQVLERRGG 73
            |..|||  .||.|:.::.....|..|.:.|::...:..|    .||.|...::|....|....|.
  Fly   338 QNRIKTNGSLPRDKNKSPFPQQAGVASSANISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGD 402

  Fly    74 GARAASPEPMKLGHRAKLRRSRSACDINE--LRGNKRTAAAPSLP-----SIPSKVSRLGG--AL 129
            |..::......|...|.:|.|....:.|.  ..|.|....:|...     ..|.|....|.  ||
  Fly   403 GGSSSGVSSNALAPTAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFAL 467

  Fly   130 TVSSQRLVRPAAPSSITAT-------AVKRPPVT--RPAP---------------------RAAG 164
            .:|..    |.|.|::.:|       ::.:||:.  .|||                     |...
  Fly   468 AISPP----PLASSAVVSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVP 528

  Fly   165 GAAAKK------------PAGTGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKVLKTK----- 212
            ...:.|            .:.|.:...|...|.||:.|.....:.|  :|:::.|.||.:
  Fly   529 AKRSNKNINNLTLNLQSVESQTQSPKPSRKPAPAPRSIHLEQRQRR--ELIQRRKQLKRELAELP 591

  Fly   213 ----YEKQTEDMGELESMPQ-----QLEETQNKLIETESSLKNTQSDNECLQRQVKQHTAKIETI 268
                .|.....:||....|.     ||:..||::...|:....|:...|..|.::||   .||..
  Fly   592 PSAGIEGLELKLGEQPLAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQ---SIEIK 653

  Fly   269 TSTLGRTKEEL----------SELQAIHEKVKTEHAAL-STEVVHLRQRTE-----ELLRCNEQQ 317
            ...|.:.:..|          .|||.:.|.::::.... ..|..:..:.:|     |..:..||:
  Fly   654 QDQLKKLRAMLKQKPNNACLKEELQLVCESLESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQR 718

  Fly   318 ---AAELETCKEQLFQSNME----------RKELHNTVM--DLRGNIRVFCRIRPPLESEENRMC 367
               .|||...:.|:.....|          ...|.|.||  .|.|:..:.|   |...::|:.|.
  Fly   719 LMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLC---PKRRNQEDLMS 780

  Fly   368 CTWTYHDESTVELQSIDAQAKS--KMGQQIF------SFDQVFHPLSSQSDIFEMVSPL---IQS 421
            .:   .:|:......|:|...:  ::..|:|      |.:|:...||.|.|.|| |:||   :.|
  Fly   781 KS---VNENMFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNLSLQGDRFE-VNPLERRVPS 841

  Fly   422 ALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNLGWE----YEIKATFL 482
            ..|....|..|.....|........:.:|:..|.|...||. :.:|::.:..|    |::|.
  Fly   842 QDDIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKLLL-AQQGHQVIEHERQKMYDLKK--- 902

  Fly   483 EIYNEVLYDLLSNEQKDME-IRMAKNNKNDIYVSNITEETVL--------DP------------- 525
            :.::|.....|.:.|:.|| .|..:::.|....:.:.|:|.|        :|
  Fly   903 KSHDEARTQYLLSTQQSMEQQRQLESDANGGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKE 967

  Fly   526 NHLRHLMHTAKMNRATAST---AGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESP 587
            |::::...|......|.:|   .|.....:.|:..:||   .||    |::|    :...||...
  Fly   968 NNVQNRKSTGSSPTTTTTTTTGGGTTPQQQRHSQPELE---HHA----IALG----IGGGGSGGA 1021

  Fly   588 KTSTRMTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQD 652
            ..:.:|....  .|.|||..|
  Fly  1022 GGANQMVARS--PRPLSEANN-------------------------------------------- 1040

  Fly   653 CFQESVKSLRFAASV-NSCKMTKAKRNRYLNNS--VANSSTQSNNSGS 697
            | ..::::.:||..: :|.....|...|..:||  .|::.:.|.||||
  Fly  1041 C-DATIEAPKFANGMDSSASPAVADNKRASSNSQDTASAGSGSGNSGS 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_476651.1	PRK03918	<204..350	CDD:235175	41/190 (22%)
		KISc_C_terminal	346..672	CDD:276817	70/366 (19%)
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	35/164 (21%)
		Caldesmon	<664..801	CDD:460421	28/142 (20%)
		PH-like	1142..1242	CDD:473070