DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and Klp3A

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001284830.1	Gene:	Klp3A / 31240	FlyBaseID:	FBgn0011606	Length:	1212	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	132/332 - (39%)
Similarity:	182/332 - (54%)	Gaps:	27/332 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 IRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFE 413
            :.|..|:||.::||.:|.|       ...||..:..|...:....:.::::.||....||.|:||
  Fly     9 VAVALRVRPLVQSELDRGC-------RIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFE 66

  Fly   414 -MVSPLIQSALDGYNICIFAYGQTGSGKTYTM----DGV-PESVGVIPRTVDLLFDSIRGYRNLG 472
             .|...::..|:|||:.|.|||||||||||||    :|| .:.||||||.|..:|.:|...:: .
  Fly    67 TCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQS-E 130

  Fly   473 WEYEIKATFLEIYNEVLYDLLSNEQKD---MEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHT 534
            :.:.:..:|:|:|.|..|||.|::.:|   ::||..||.   |.:..:||..|.....:...:..
  Fly   131 FRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNR---IIMPGLTELVVTSAQQVTDHLIR 192

  Fly   535 AKMNRATASTAGNERSSRSHAVTKLELIGRHAE-KQEISVGSINLVDLAGSE-SPKT---STRMT 594
            ....||.|:||.||.||||||:..|.|:....: ||.::....||||||||| ..||   ..|..
  Fly   193 GSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRFK 257

  Fly   595 ETKNINRSLSELTNVILAL--LQKQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQES 657
            |..|||:.|..|.|||.||  .|...:||||.||||.||..||||||.|||...|||......|:
  Fly   258 EGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAET 322

  Fly   658 VKSLRFA 664
            :.:||:|
  Fly   323 LSTLRYA 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	132/332 (40%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	132/332 (40%)
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	132/332 (40%)
		Kinesin	14..335	CDD:278646	131/327 (40%)
		Smc	<396..>994	CDD:224117
		FlaC	522..633	CDD:225888
		TCR	1075..1110	CDD:281618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840